Based on the pseudo-temporal reconstruction of these data, we map the transcriptional variation of the innate immune response at single-cell resolution. This provides the foundation for superimposing human genetic variation onto the transcriptional dynamics of this response. To this end, we develop a...
Genome-wide association studies in combination with single-cell genomic atlases can provide insights into the mechanisms of disease-causal genetic variation. However, identification of disease-relevant or trait-relevant cell types, states and trajectories is often hampered by sparsity and noise, particula...
Ignore dataComparator change in props diff (#6669) fix(mapbox) leave additional views intact (#6329) fix(tets): include Typescript sources in test coverage (#6663)deck.gl [8.7.0-beta.6] - Feb 21 2022CARTO: Rename CartoDynamicTileLayer -> CartoTileLayer (#6658) GeoJsonLayer[binary]: ...
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Martin Luther King Jr. Day celebrations have kicked off at King's former congregation in Atlanta with a 70-member choir's rendition of Hallelujah and stern words from his youngest daughter warning against anti-woke rhetoric Associated PressJan. 20, 2025...
Empty Cell GEOTRACES South Pacific (GSP) SAFe D1a NADW Elements Determined n Consensus Determined n Consensus Determined n Mn (nmol/L) 0.787 ± 0.011 14 0.778 ± 0.034 0.421 ± 0.006 3 0.443 ± 0.005 17 Fe (nmol/L) 0.150 ± 0.009 13 0.155 ± 0.045 0.722 ± 0.008 3 0.69 ± 0.04 0.5...
It can capture the spectral diversity across images and has been applied in rangelands to map ecosystem degradation caused by overgrazing and improper management (Tanser and Palmer 1999; Jafari et al. 2008). Another example is the Leakiness Index (LI) (Bastin et al. 2002; Ludwig et al. ...
Table S1. Previous single-cell studies; donor characteristics; snRNA-seq and snATAC-seq data and quality control metrics, related to Figures 1 and 5 Table S2. Subcluster membership in major clusters and developmental trajectories; hotspot modules; and IN subcluster investigation, related to Figures...
We engineered proteins to capture single-stranded DNA (ssDNA) ends with 3′ polarity in bacterial and human cells. In Escherichia coli, spontaneous 3′-ssDNA-end foci were unexpectedly frequent, at one or more per cell division, and arose via two identifiable pathways, both of which were ...
a computational framework to identify and characterize cell niches from spatial omics data at single-cell resolution - ZJUFanLab/scNiche