Astrocytoma is one of the most common primary central nervous system tumors and has both high mortality and a poor 5-year survival rate. MicroRNAs (miRNAs) play important roles in carcinogenesis by acting on multiple signaling pathways. Although we have demonstrated that miR-137 is downregulated in...
(86% long-term survival for children and adolescents younger than 20 years versus 33% for those 20 years old or older) and the degree of tumor involvement, reflected by the neurologic deficit and the extent of resection (37% survival rate for patients after biopsy or limited removal compared...
Pilocytic astrocytoma (PA) is the most common pediatric brain tumor in children. PAs are a distinct histologic and biologic subset of glioma that have a slow growth rate and may even spontaneously regress. These tumors tend to arise in the cerebellum and chiasmatic/hypothalamic region, but can ...
After gross local resection, the likelihood of recurrence is low (10–20%), while the 10-year overall survival rate is high (up to 96%). Despite this, clinicians have little understanding of the pathogenesis of pilocytic astrocytoma. Researchers believe that characterizing the proteome of the ...
Oligoastrocytomas and pureoligodendrogliomasconstitute a subgroup ofbrain tumorsreceiving increased attention because of reports of chemosensitivity and of favorable survival rate when compared withastrocytomas. This is also reflected in the increasing rate of diagnosis of tumors with an oligodendroglial com...
The actual survival rate was 54.8% at 5 years after diagnosis. So stereotactic radiation ther- apy may offer a more appropriate and effective alter- native in the treatment of these tumours, Chemotherapy has not been given in our series. To the best of our knowledge no larger series with ...
Doctors firstsurgically removeas much of the tumor as is safely possible. Radiation therapyincreases the rate of survival and is usually done after surgery. Chemotherapydoes not seem to increase the rate of survival, but, in some children, it may help shrink the tumor before surgery or radiation...
Chemotherapy does not seem to increase the rate of survival, but, in some children, it may help shrink the tumor before surgery or radiation therapy. Prognosis for Ependymomas How well the child does depends on the child's age, type of ependymoma, and on how much of the tumor can be ...
Pilocytic astrocytoma is the most common brain tumor in children. It is a WHO (World Health Organization) grade 1 tumor that does not progress to a higher grade in most cases, and for which the 10-year survival rate among patients is 96%.26 However, neither the pathogenesis nor the ...
Define astrocytomas. astrocytomas synonyms, astrocytomas pronunciation, astrocytomas translation, English dictionary definition of astrocytomas. n. pl. as·tro·cy·to·mas or as·tro·cy·to·ma·ta A malignant tumor of nervous tissue composed of astroc