In an effort to develop novel anti-coronavirus therapeutics and achieve prophylactics, we used gene set enrichment analysis (GSEA) for drug screening and identified that Astragalus polysaccharide (PG2), a mixture of polysaccharides purified from Astragalus membranaceus, could effectively reverse...
ASTRAGALUS MONGHOLICUS ROOT POLYSACCHARIDES 反馈纠错 帮助中心 打印 UNII号 71WW2LNL50 化学名 ASTRAGALUS MONGHOLICUS ROOT POLYSACCHARIDES 结构式图片 ITIS 820171 NCBI 119829 PLANTS ASMO18 GRIN 402528 别名 PG2;PG-2;ASTRAGALUS MEMBRANACEUS ROOT POLYSACCHARIDES;ASTRAGALUS POLYSACCHARIDES...
them, the anticancer effect is the most prominent. In short,Astragaluspolysaccharide is a valuable immunomodulatory medicine, but further high-quality studies are warranted to corroborate its clinical efficacy.
Fig. 2. Schematic presentation of the biological mechanisms of main bioactive compounds in AM (Astragaloside-I, II, -IV, Iso-astragaloside-I, Flavonoids, Astragalus Polysaccharides, Astragalus Polysaccharides 4, AI) on Neurodegenerative diseases (Alzheimer’s disease and Parkinson’s disease); Diabetes...
(2 g/ram/day) compared to the APS group (20 g/ram/day). Understanding the mechanistic action may be out of the scope of this study. Astragalus polysaccharides lack significant activity because it is difficult to penetrate cell membranes or some of them are absorbed from the cell interstitial...
Astragalus polysaccharides resulted in a reduction in cellular apoptosis through the modulation of Bcl-2/Bax ratio and the prevention of pro-apoptotic protein expression in both intrinsic and extrinsic pathways (Sun et al. 2017). Table 2 Summary of reported activities for A. membranaceus Full size...
Three groups of chemicals have been described as pharmacologically active principles: polysaccharides, saponins and phenolics. In addition, three kinds of toxic principles have been reported: indolizidine alkaloids, aliphatic nitro compounds and selenium. 1997 John Wiley & Sons, Ltd. 展开 关键词:...
polysaccharidesMesenchymalstemcellsPG2ProliferationImmunosuppressionEthnopharmacological relevance Astragalus membranaceus is used to manage the deficiency of vital energy in traditional Chinese medicine and confirmed to have many biological functions. Mesenchymal stem cells (MSCs) possess immunosuppressive effects, ...
polysaccharidesindolizidine alkaloidsSome Astragalus species are used as forage for livestock and wild animals. Many species are used in folk medicine for their hepatoprotective, antioxidative, immunostimulant, and antiviral properties, whereas others are toxic, and in many cases the toxic principles can ...
Astragalus polysaccharidesMesenchymal stem cellsPG2ProliferationImmunosuppressionEthnopharmacological relevance: Astragalus membranaceus is used to manage the deficiency of vital energy in traditional Chinese medicine and confirmed to have many biological functions. Mesenchymal stem cells (MSCs) possess ...