Victoria Hammersley1, Rebecca Knibb2, Bertine Flokstra-de-Blok3,4, Audrey DunnGalvin5, Samantha Walker1,6, Anthony EJ Dubois3,7 and Aziz Sheikh1,8 BACKGROUND: Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer....
Victoria Hammersley1, Rebecca Knibb2, Bertine Flokstra-de-Blok3,4, Audrey DunnGalvin5, Samantha Walker1,6, Anthony EJ Dubois3,7 and Aziz Sheikh1,8 BACKGROUND: Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the...
Substance misuse is associated with poor asthma outcome and death. People with opioid use disorder (OUD) may be at particular risk, however, there have been no case-control studies of asthma care and outcomes in this patient group. A primary care databas
Amy Van Dyken is another example. She was diagnosed with severe asthma at a very young age and at her doctors’ suggestions she started getting involved with sports to make her lungs strong. Her main sport was swimming and in spite of being an asthma patient she managed to succeed and won...
RAPID is being conducted in accordance with the Declaration of Helsinki, the International Conference on Harmonisation Good Clinical Practice guideline, and applicable regulatory requirements. The RAPID protocol was reviewed and approved by the respective institutional review boards before patient recruitment....
38 To compare meta-analysis of aggregate severe exacerbation outcome data with patient-level time-to-event data, we digitized Kaplan-Meier curves and extracted patient-level data,39,40 confirmed fidelity to values in original study reports, validated proportional hazards assumptions, fitted a shared ...
Current asthma was ruled out in 203 of 613 study participants (33.1%; 95% CI, 29.4%-36.8%). Patient Characteristics Associated With Exclusion of Current Asthma Table 1 shows the baseline characteristics of the 203 participants in whom current asthma was ruled out, compared with the 410 ...
It is also important to consider the differences in duration of exposure to study drug across the five studies, in particular, the markedly lower number of patient-years of exposure to placebo that limits the ability to directly compare safety data. In addition, differences in study design ...
From a patient’s perspective, these are simple aims, but for the purposes of study design and treatment trials they do not address the complexity of the disease process. Accordingly, guidelines now specifically address asthma control (symptoms and lung function) and severity (need for treatment)...
BMC Pulmonary Medicine (2023) 23:21 https://doi.org/10.1186/s12890-022-02293-4 BMC Pulmonary Medicine RESEARCH Open Access Implementing the Patient Needs in Asthma Treatment (NEAT) questionnaire in routine care: a qualitative study among patients and health professionals Julia ...