While ALT is predominantly found in the liver, meaning its elevation is a more direct sign of liver damage, AST is not exclusive to the liver. AST can also be found in significant amounts in the heart, muscles, and kidneys. 11 In medical tests, the ratio of ALT to AST can be essenti...
Liangpunsakul S,Qi R,Crabb DW,et al.Relationship between alcohol drinking and aspartate aminotransferase:alanine aminotransferase(AST:ALT)ratio,mean corpuscular volume (MCV),gamma-glutamyl transpeptidase (GGT),and apolipoprotein A1and B in the U.S.population.J Stud Alcohol Drugs. 2010...
genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G×E interaction analysisLiver tests (LT), especially to measure AST, ALT and GGT levels, are widely used to evaluate the risk of alcohol-related liver disease (ALD)....
One test your doctor might do along with the AST test is the alanine transferase (ALT) test. ALT is also a type of enzyme, but unlike AST, it is found mostly in your liver. Your doctor might want to measure both of these because they can leak into your bloodstream when you have dama...
Fig. 3: Comparison of effect of lead variants on ALT and AST with effect on liver disease. Effect sizes (beta from the regression of units of log10ALT and AST, equivalent to percent change; and beta from the liver disease regression, equivalent to natural log of the odds ratio) are from...
doi:10.1016/S0016-5085(09)63929-9Liangpunsakul, SuthatQi, AmyElsevier Inc.GastroenterologyLiangpunsakul S, Qi R, Crabb Dw et al. Relationship between alcohol drinking and AST:ALT ratio, GGT in the US population. J Stud Alcohol Drugs 2010 Mar 71(2):249- 52...
The AST: ALT and GGT: Alkaline Phosphatase Ratios as Indicators of Alcohol-induced Liver Enzyme Elevations in a Community-based Working PopulationUpfal, Mark J.Gurney, JamesJournal of Occupational and Environmental Medicine
Diagnostic value of AST, ALT, amylase, and lipase in differentiating gallstones from alcohol induced pancreatitisdoi:10.1016/S0002-9270(01)03039-8Urooj Ahmed and Affan Quadri and Jerry Jacobsen and Aboud AffiThe American Journal of Gastroenterology...
The AST: ALT and GGT: Alkaline Phosphatase Ratios as Indicators of Alcohol-induced Liver Enzyme Elevations in a Community-based Working Population.UpfalMark JGurneyJames
and PDE9A genes that appeared to impact both AST and ALT levels in the context of the reported alcohol consumption.DiscussionGenomic location of our top association findings indicates their potential involvement in the essential cellular function, which may also be relevant for alcohol-related liver ...