White blood cell (WBC) count, hemoglobin (Hgb), hemoglobin F (HbF) were also stratified by hydroxyurea use to establish baseline hematologic characteristics. Medians were compared using the Mann-Whitney U test. Results There were 68 sickle cell patients with complete, steady-state laboratory data...
weight, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured in all subjects. Body mass index (BMI) was computed according to the formula of weight in kilograms divided by the square of height in meters (kg/m2). After fasting overnight, blood specimens were collec...
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concentration of α-ketoglutarate. This ratio was four to one (in this case, 4 mM aspartate to 1 mM α-ketoglutarate). This difference can be explained by a stronger complex of AST-α-KG and the fact that the concentration of α-KG is partially restored due to the work of glutamate ...
1. Introduction Aspartate aminotransferase (AST, EC 2.6.1.1) and alanine aminotransferase (ALT, EC 2.6.1.2) are enzymes found mainly in the liver, but also found in red blood cells, heart cells, muscle tissue and other organs, such as the pancreas and kidneys. AST and ALT formerly are ...