Here we demonstrate that the large language model GPT-4 can accurately annotate cell types using marker gene information in single-cell RNA sequencing analysis. When evaluated across hundreds of tissue and cell types, GPT-4 generates cell type annotation
This capability can considerably reduce the effort and expertise required for cell type annotation. Additionally, we have developed an R software package GPTCelltype for GPT-4's automated cell type annotation.doi:10.1038/s41592-024-02235-4Hou, Wenpin...
在这里,我们证明大语言模型 GPT-4 可以在单细胞 RNA 测序分析中使用标记基因信息准确注释细胞类型。 当对数百种组织和细胞类型进行评估时,GPT-4 生成的细胞类型注释与手动注释表现出很强的一致性。 此功能可以大大减少细胞类型注释所需的工作量和专业知识。 此外,我们还为 GPT-4 的自动细胞类型注释开发了 R 软件...
During the preparation of this work the author(s) used Grammarly and ChatGPT in order to check the grammar and improve clarity. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the publication. Declarati...
NA: No gene annotation for the transcript. * Pfam result: protein containing the specified domain. Adjusted p-Value 7.17 × 10−78 1.18 × 10−55 1.56 × 10−28 3.14 × 10−25 1.11 × 10−24 1.25 × 10−22 3.27 × 10−22 4.67 × 10−21 5.52 × 10−20 2.13 × ...