a diagnostic assay able to accurately identifyP. simiumis important for malaria surveillance. Based on mitochondrial genome sequences, primers were designed to amplify a region containing a SNP specific toP. simium. This region can then be digested with the restriction enzymeHpyCH4III, which result...
自2006年1月成立以来,Assay生物技术一直是全球抗体生产和工程检测技术、荧光染料、猝灭剂、重组蛋白和合成肽的贡献者 自2006年1月成立以来,Assay生物技术一直是抗体生产和工程检测技术、荧光染料、猝灭剂、重组蛋白和合成肽的贡献者。位于加州鈥檚旧金山湾区的中心地带,我们一直致力于满足全球对高质量检测试剂盒和用于医药...
that is consistent across usp–nf’s suite of bioassay chapters, is complementary to previous authoritative usage, and provides a useful focus on the bioassay context. in many cases the terms cited here have common, though undocumented, usages or are defined in validation of compendial procedures ...
Drug resistance is associate with mutations in the RT region.The virus is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes presented on its envelope proteins, and into nine genotypes (A-I) according to overall nucleotide sequence variation of the genome. ...
by adopting 2 standard deviations from the mean, any test values which fall outside of the calculated range are said to be atypical values and not representative of the normal population. On this basis, the LAL test requires investigation. As a way of a further check on technician ...
The disproportionate effect on factor IIa in part forms the basis for the current USP monograph test which specifies that the ratio of anti-Xa activity to anti-IIa potency should fall between 0.9 and 1.1. In this work, we examine the utility of 1H NMR, SAX-HPLC, and anticoagulation time ...
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When there is an existing product specification, acceptance criteria can be justified on the basis of the risk that measurements may fall outside of the product specification. Considerations from a process capability (Cp) index can be used to inform bounds on the relative bias (RB) and the IP...
A method of diagnosing the source of local, acute inflammation has been developed based on the discovery that white cells have different patterns of gene expression, and therefore p
Abstract Deubiquitylating enzymes (DUBs) play a vital role in the ubiquitin pathway by editing or removing ubiquitin from their substrate. As breakthroughs within the ubiquitin field continue to highlight the potential of deubiquitylating enzymes as drug targets, there is increasing demand for versati...