High-dose aspirin monotherapy superior to low-dose aspirin + warfarin in post-MIInpharma Weekly -doi:10.2165/00128413-200113110-00023NoneSpringer International PublishingInpharma Weekly
Background鈥擜spirin is the most widely used antiplatelet drug post-myocardial infarction (MI), yet its optimal maintenance dose after percutaneous coronary intervention (PCI) with stenting remains uncertain.Methods and Results鈥擶e compared outcomes of 10,213 MI patients who underwent PCI and were ...
Tertiary prevention (post-MI) Aspirin 81 mg orally daily Similar efficacy in coronary disease prevention as the 325 mg dose Half the risk of gastrointestinalHemorrhageas the 325 mg dose References Eikelboom (2012) Chest 141(2 Suppl):e89S-119S [PubMed] ...
Initial dose: 160 to 162.5 mg orally once as soon as myocardial infarction is suspected Maintenance dose: 160 to 162.5 mg orally once a day for 30 days post-infarction Comments: Extended-release products should not be used when a rapid onset of action is desired such as suspected MI; non-...
Body weight and body weight gain were reduced and neurobehavioral or general developmental delays in the immediate post-weaning timeframe were evident at doses equal to or greater than 69 mg/kg/day (about 17 times an oral human dose of 40 mg esomeprazole or 40 mg omeprazole on a body ...
However, the effects of the addition of clopidogrel in pa-tients who have MI with ST-segment elevation (STEMI) and who are receiving or not a standard fibrinolytic regimen, including aspirin, and/or who may undergo PCI remain unclear. The pretreatment with a loading dose and the timing of ...
Available data from published studies and postmarketing experience with AGGRENOX use during pregnancy have not identified a clear association between AGGRENOX use and major birth defects, miscarriage, or adverse maternal or fetal outcomes (see Data). AGGRENOX contains low-dose aspirin which is an NSAID...
infarction in men,with little effect on the risk of ischaemic stroke.Conversely,new data have shown that,in women,low-dose aspirin lowers the risk of stroke,but does not affect the risk of MI or death from all cardiovascular causes... The Pharmaceutical Journal Group - 《Pharmaceutical Journal...
Low‐dose aspirin for secondary cardiovascular prevention – cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation – review and meta‐analysis J Intern Med, 257 (2005), pp. 399-414 CrossrefView in ScopusGoogle Scholar 31. Mantz J., Samama C.M., Tu...
A published clinical study involved six exclusively breastfeeding women at 1 to 8 months postpartum who were taking 81 mg aspirin daily. Milk samples were collected at steady state, at 0, 1, 2, 4, 8, 12, and 24 hours after taking a dose of aspirin. Aspirin was undetectable in human ...