While prospective and randomized study are currently investigating the effect of aspirin in prevention of both cancer and CVD, clinical efforts at the individual level to promote the use of aspirin in global (or total) primary prevention could be already based on a balanced evaluation of the ...
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Aspirin alone is indicated in the setting of the primary prevention of coronary heart disease in individuals who have multiple coronary risk factors. It is also recommended for the secondary prevention of ischemic stroke, patients with symptomatic peripheral arterial disease, and the long-term secondary...
A Prospective Study of Aspirin Use and Primary Prevention of Cardiovascular Disease in Women JoAnn E. Manson, MD; Meir J. Stampfer, MD; Graham A. Colditz, MB, BS; et al Walter C. Willett, MD; Bernard Rosner, PhD; Frank E. Speizer, MD; Charles H. Hennekens, MD Author Affiliations...
"We're not saying that nobody should be having aspirin for primary prevention, but after 20 years of evidence [showing little to no benefit and possible harm] of aspirin in primary CV prevention, we believe the decision to take aspirin for primary prevention is something you should discuss wi...
Hennekens CH, DeMets DL. Prevention: Aspirin in primary prevention needs individual judgements. Nat Rev Cardiol. 2014; 11(8):438-40. doi: 10.1038/nrcardio.2014.88 PMID: 24958081Hennekens CH, DeMets DL. Prevention: Aspirin in primary prevention needs individual judgements. Nat Rev Cardiol. 2014...
Randomized evidence for aspirin in the primary prevention of cardiovascular disease (CVD) among women is limited and suggests at most a modest effect for total CVD. Lack of compliance, however, can null-bias estimated effects. We used marginal structural models (MSMs) to estimate the etiologic ef...
In light of this new evidence, the ACC/AHA guidelines recommend aspirin for primary prevention in patients 40-70 years of age at a high ASCVD risk and low bleeding risk, who are unable to optimally control modifiable ASCVD risk factors....
Low-dose aspirin has proven effectiveness in secondary and primary prevention of cardiovascular events, but is also associated with an increased risk of major bleeding events. For primary prevention, this absolute risk must be carefully ... RLA García,MP Mar,CH Hennekens,... - 《Plos One》 ...
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