The role of aspalathin in limiting the progression of metabolic disorders and preventing diabetes-induced cardiovascular complications has been reported. The aforementioned potential health benefits of aspalathin have rendered it a popular natural ingredient that is incorporated in various nutraceutical and...
Together, all of these effects make the body less susceptible to type-2 diabetes. In addition, these benefits can be useful for patients who already have the disease. Aspalathin prevents sudden drops and spikes in blood sugar that would be dangerous to diabetic patients. Aspalathin is noted ...
Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Aspalathin (Asp) and nothofagin (Not) are two major active dihydrochalcones found in green rooibos, which have been reported for their antioxidant activity. In ...
type 2 diabetescardiovascular risk factorsantidiabetic activityaspalathin-enriched green rooibos extractcoenzyme Q(10)Type 2 diabetic patients possess a two to four-fold-increased risk for cardiovascular diseases (CVD). Hyperglycemia, oxidative stress associated with endothelial dysfun...
Aspalathus linearisType 2 diabetesdb/db miceMyotubesPancreatic β-cellEffects of aspalathin, a green rooibos tea component, on glucose metabolism were studied in vitro and in vivo. We first examined the effect of aspalathin on glucose uptake by cultured L6 myotubes and on insulin secretion from...
DiabetesCardiomyopathyFatty acid oxidationScopeEnergy deprivation in the myocardium is associated with impaired heart function. This study aims to investigate if aspalathin (ASP) can ameliorate hyperglycemic-induced shift in substrate preference and protect the myocardium against cell apoptosis.Johnson, Rabi...
The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus. Surfaces Interfaces 2021, 2, 101251. [CrossRef] 18. Badeggi, U.M.; Ismail, E.; Adeloye, A.O.; Botha, S.; Hussein, A.A. Green Synthesis of Gold Nanoparticles Capped with Procyanidins from ...
diabetesglucotoxicityoxidative stressScope Aspalathin, the main polyphenolic phytochemical of rooibos ( Aspalathus linearis ), has been attributed with health promoting properties, including a glucose lowering effect that can prove interesting for application as nutraceutical or therapeutic in (pre‐)...
Vascular inflammation plays a key role in the initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Aspalathin (Asp) and nothofagin (Not) are two major active dihydrochalcones found in green rooibos, which have been reported for their antioxidant activity. In ...