该笔融资将用于推进Asceneuron的主打项目ASN51进入治疗阿尔茨海默病的2期临床开发阶段。ASN51是一种口服小分子药物,旨在抑制与蛋白质聚集有关的酶OGA。通过阻止tau蛋白的聚集,以减缓阿尔茨海默病的进展。OGA抑制还显示出阻止其他神经退行性疾病(包括帕金森病和肌萎缩侧索硬化)的核心蛋白质聚集的潜力。 ASN51独特的作用...
AS9036 NEURONNEXION-AS - Neuronnexion SCOP 6912 AS31328 SCHNEIDER-AS - SCHNEIDER ELECTRIC INDUSTRIES SAS 6912 AS31221 EUCLYDE - nLighten France SAS 6912 AS199483 LINKER-AS - NXO France SAS 6656 AS203058 TIMS - TIMS Systemes SAS 6656 AS198335 TRANSATEL - TRANSATEL SAS 6656 AS35676 LA-POST...
Chicken SMN1(Survival of Motor Neuron 1, omeric) ELISA Kit Chicken ENG/CD105 (Endoglin) ELISA Kit Chicken TNX (Tenascin X) ELISA Kit Chicken CXCR3 (Chemokine CXC Receptor 3) ELISA Kit Chicken F12 (Coagulation Factor Ⅻ) ELISA Kit Chicken GSANA (Granulocyte Specific Anti-Nuclear Antibody)...
Acid-sensing Ion Channels (ASIC)Allosteric RegulationIon ChannelsNeuronReceptor DesensitizationNeurons of the mammalian nervous system express the proton-sensing ion channel ASIC1. Low concentrations of protons in the normal range of extracellular pH, pH 7.4–7.3, shut the pore by a conformational ...
CAS号: 英文名: NEURON SPECIFIC PEPTIDE 英文别名: NEURON SPECIFIC PEPTIDE;ASP-VAL-SER-ASP-GLY-SER-ALA-GLU-ARG-ARG-PRO-TYR-THR-ARG-MET-GLY-SER-GLY-GLY-LEU-LYS-LEU-HIS-CYS-VAL-HIS-PRO-ALA-ASN-CYS-PRO-GLY-GLY-LEU-MET-VAL-THR
基本信息 药品名称 ASN51 药品类别 创新药; 化药; 小分子 靶点 O-GlcNAcase (OGA) 作用机制 OGA抑制剂 药品简介 -- 研发机构 Asceneuron 最高研发阶段 全球: I期临床 中国: 临床前 审评审批类型 -- 外置链接 -- 了解药物更多情报 登录查看 生物序列 研发时光轴 交易&权益 疾病 获批适应...
This protocol details a method for analyzing the expression of multiple genes from a single Purkinje neuron, including the determination of whether the gen... ShyuksumAsrachsproocodasamhodforanayznhprssonofmupnsfromasnPurknjnuron,N Hproocodscrshoworacasn,vnPurknjcforrvrsranscrpon,... - 《Na...
Similar results on the ability of VIP(6-28) to block VIP-stimulated increases in cAMP levels are obtained in neuron-enriched and in non-neuronal cell-enriched dissociated cultures. 参考质量标准外观:白色粉末纯度(HPLC) ≥98.0%醋酸根含量≤12.0%水分含量≤8.0%肽含量≥80.0%内毒素≤50EU/mg氨基酸...
Article: Asn-265 of frog kainate binding protein is a functional glycosylation site: Implications for the transmembrane topology of glutamate recep
Researchers develop an easily scalable approach for fabricating cholesteric liquid-crystal elastomer films. Speeding up neuron growth with a phage Apr 23, 2020|Regenerative Medicine A platform with a unique hierarchical nanoridge-in-microridge structure supports the rapid growth of neural cells. ...