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silico molecular docking analyses of FIASMAs with inhibitors revealed that dilazep (S = − 12.58 kcal/mol), emetine (S = − 11.65 kcal/mol), pimozide (S = − 11.29 kcal/mol), carvedilol (S = − 11.28 kcal/mol), mebeverine (S = − 11.14 k...
When testing whether overexpressing PMEs in planta might also affect cell adhesion, we found that alcohol-inducible overexpression of AtPME5 stunted seedlings (Peaucelle et al., 2008) but did not promote lesion formation in 6-d-old etiolated seedlings after 3 or 6 d of induction (Fig. 4E-F...
NetEase Games is dedicated to delivering the highest quality of products, suitable for the game industry worldwide. NetEase is excited to launch open beta testing for Kung Fu Panda, the mobile action adventure game, on November 26, 2015. The game will be an eye-catching addition to NetEase'...
No values were imputed for zeros, no multiple testing corrections were applied as the analysis relied on multiple criteria beyond p-value to establish significance. Electron cryo-microscopy UltrAuFoil R1.2/1.3 Au300 mesh grids (Quantifoil) were glow discharged for 1 min on each side at 25...
these cells are not suitable for testing any potential effect of dysferlin on muscle cell differentiation. However, our finding, across all these mouse and human cellular models, that dysferlin deficiency causes poor repair of dysferlinopathic myoblasts makes these cells an excellent model for screenin...
Therefore, predicting enzymatic activity is critical before the administration of FPs, in which in vitro testing has proven to be a useful complementary method to in vivo testing. This review summarized the findings on the functional characterization of DPD, DHP, and β-UP using in vitro analysis...