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This discovery provides answers for the long-standing question of whether and how BRCA1 uses its E3 ligase activity to maintain the genome stability and suppress tumorigenesis, and unveils a DDR pathway centered on 7SK snRNP. Results LARP7 Deficiency Attenuated the DNA Damage Response Ionizing ...
(1) past-year or lifetime experiences of racial discrimination in the workplace and job-related stress predicted depressive symptoms; and (2) controlling for depressive symptoms, past-year and lifetime racial discrimination at work correlated with job-related stress in a sample of Black registered...