Therapeutic Class: Parenteral VitaminPharmacologic Class: Vitamin C (class)More about ascorbic acid Check interactions Compare alternatives Reviews (8) Drug images Latest FDA alerts (2) Side effects Dosage information During pregnancy Drug class: vitamins Breastfeeding Patient resources Ascorbic acid drug ...
Ascorbic acid (AA, vitamin C) has shown a potential anti-cancer therapeutic activity in several cancers. However, the anti-cancer effects of ascorbic acid on CLL B-cells have not been extensively studied. We aimed in this study to evaluate the in vitro therapeutic activity using clinically ...
BCS Class1 Stability:Stable. May be weakly light or air sensitive. Incompatible with oxidizing agents, alkalies, iron, copper. InChIKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N LogP-1.85 CAS DataBase Reference50-81-7(CAS DataBase Reference) NIST Chemistry ReferenceL-Ascorbic acid(50-81-7) ...
Ascorbic acid (AA) enhances the activity of TET2 likely by reducing catalytic site Fe(III) to Fe(II)21,22. Simultaneous 2-oxoglutarate decarboxylation provides two additional electrons needed for dioxygenase activity. AA may thus improve the function of intact TET2 in cases with heterozygousTET2MT,...
The history of ascorbic acid (AA) and cancer has been marked with controversy. Clinical studies evaluating AA in cancer outcome continue to the present day. However, the wealth of data suggesting that AA may be highly beneficial in addressing cancer-asso
AA enhances anti-PD1 HCC therapeutic effect by increasing CD11b+ CD44+ PD-L1+cell population infiltration Since AA could alleviate liver injury, we needed to consider its effect on tumor growth to avoid its counterproductive effect. For addressing the possible effect exerted by AA for HCC tumors...
Biochemical changes associated with ascorbic acid–cisplatin combination therapeutic efficacy and protective effect on cisplatin-induced toxicity in tumor-bearing mice 文档格式: .pdf 文档大小: 4.32M 文档页数: 15页 顶/踩数: 0/0 收藏人数: 0
Keeping in view the fact that LXR-± plays crucial role in keratinocyte proliferation and differentiation, it becomes imperative to dissect the pathways and role of LXR-± genomics in the pathogenesis of psoriasis with ultimate aim to explore novel preventive/therapeutic strategies as treatment options...
Partial hydrolysis with aqueous HCl gave deprotected 2-oxo-L-gulonic acid, which yielded ascorbinic acid by heating with HCl. Therapeutic Function Vitamin General Description Different sources of media describe the General Description of 50-81-7 differently. You can refer to the following data: 1...
Ascorbic acid also exerts varying effects on catalase activity depending on cell type, notably enhancing it in keratinocytes at concentrations around 100 μM. These multifaceted actions underscore the potential therapeutic implications of ascorbic acid in conditions associated with oxidative stress [93]. ...