Using IHC, we showed a significantly higher expression of NOTCH3 and NOTCH1 intracellular domain (ICD), the ligands JAG1, JAG2, and DLL4 and a higher tendency for NOTCH4 expression (P = 0.0571) in intima-media of BAV-ND compared to TAV-ND (Fig. 8a-l). However, the NOTCH ...