ASC30 was discovered and developed in-house atAscletisas a GLP-1R biased small molecule agonist without β-arrestin recruitment. ASC30 has unique and differentiated properties that enable the administration of one small molecule as both a once-monthly subcutaneous injection and a once-daily oral tab...
ASC has a bipartite domain structure, consisting of an N-terminal pyrin domain (PYD) and a C-terminal caspase-recruitment domain. The PYD of ASC (ASC_PYD) is known to interact with various PYD-containing intracellular danger signal sensors and PYD-only proteins. Using purified proteins, we ...
Downstream of NLRs, ASC plays an important role in the assembly of inflammasomes and the recruitment of caspase-123. To investigate the potential role of ASC in propofol-induced pyroptosis, another macrophage cell line, RAW264.7, was used, as ASC is deleted in this cell line. As shown in Fi...
39,735 点评 薪资 20 招聘 常见问题解答 面试 172 照片 想来这工作吗? 查看职位 点评此公司 职位名称 不限 地点 Quezon City908 条点评 按类别评分 3.2工作-生活平衡 3.2薪资与福利 3.1职位安全与晋升 3.0管理方式 3.2企业文化 搜索评价 搜索 排序方式 ...
职位名称 Site Manager116 条点评 地点 不限 按类别评分 3.6工作-生活平衡 3.3薪资与福利 3.1职位安全与晋升 3.4管理方式 3.5企业文化 搜索评价 搜索 排序方式 评分时间 语言 已找到符合搜索的116条评价查看 18,871 条评论 2.0 Unfair on a lot of things ...
4.0工作-生活平衡 4.1薪资与福利 3.6职位安全与晋升 3.7管理方式 4.0企业文化 搜索评价 搜索 排序方式 评分时间 语言 已找到符合搜索的90条评价查看 8,182 条评论 1.0 Great total rewards! But not for long term employment! Global Services HR(在职员工)-Parañaque City-2020年11月20日 ...
Recruitment Coordinator(离职员工)-Bonifacio City-2024年7月27日 Has a great company culture and a lot of learning opportunities. Mobility is encouraged and career growth is present - albeit slow. Overall a good company to work with especially as a fresh graduate. ...
不限 地点 不限 按类别评分 3.4工作-生活平衡 3.3薪资与福利 3.1职位安全与晋升 3.3管理方式 3.5企业文化 搜索评价 搜索 排序方式 评分时间 语言 正在显示唯一的评价 4.0 fun workplace, suitable hours call centre advisor(离职员工)-liverpool-2014年3月5日 ...