公司最先聚焦在异体细胞治疗上, ASC Therapeutics开发同种异体蜕膜基质细胞(DSC),并搭建了ASC-930管线,用以治疗类固醇难治性移植物抗宿主病(SR-aGvHD)。 目前,该管线也成为ASC Therapeutics进展最快的管线,公司正在美国进行该疗法的临床Ⅱ期试验。姜儒鸿博士也表示,ASC-930的快速进展推进了对ASC Therapeutics系列平台...
目前,公司主要拥有三个管线产品,分别为基因替代治疗 (ASC-618),基因编辑治疗(ASC-518)甲型血友病,和异体干细胞治疗(ASC-930)类固醇难治性移植物抗宿主病(SR-aGvHD) 。项目ASC-618和ASC-930将于2021第二季度分别进入临床I/IIa期和临床IIb期的研究。 公司计划在中国建立全球领先的基因编辑和细胞治疗的GMP生产基地...
抗体分泌细胞 (ASC) 在活化后分化,可分泌各种可溶性同种型免疫球蛋白受体。ASC 主要在次级淋巴器官的生发中心内产生(尽管滤泡外反应也可能产生 ASC)。抗原暴露后,活化B细胞的主要调节基因下调,ASC转录程序上调,从而驱动B细胞分化为早期ASC或浆母细胞。浆母细胞是一种...
Minerals and biological assets including timber (ASC 930, 932) Inventory (ASC 330) Assets under construction (Covered under ASC 360) How has lease classification changed under ASC 842? Besides renaming capital leases “finance leases”, ASC 842 added a fifth lease classification question (...
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Leases for the exploration or use of non-regenerative natural resources such as oil, natural gas, and minerals are covered under ASC 930,Extractive Activities – Mining, and ASC 932, Extractive Activities – Oil and Gas. Leases of biological assets such as plants, animals, and timber. These ...
930 208 MC015 迈克基阿罗酒庄拉克特山阿斯蒂巴贝拉特酿法定产区干红葡萄酒 Michele Chiarlo Barbera d’Asti La Court DOCG 464 700 MC017 迈克基阿罗酒庄山中云阿斯蒂莫斯卡微泡保证法定产区甜白葡萄酒(低醇葡萄酒) Michele Chiarlo Nivole Moscato D Asti DOCG 375ml 2796 160 MC024 迈克基阿罗酒庄佳味保证法定产...
•Changes in regulatory assets and liabilities arising from alternative revenue programs for rate-regulated activities in the scope of ASC 930, Regulated Operations The guidance included in new subtopic ASC 340-40 applies only if the costs are incurred related to a contract under ASC 606. (ASC ...
Entertainment - Cable TelevisionASC专题922“娱乐业—有限电视”ASC Topic 924 Entertainment - CasinoASC专题924“娱乐业—赌场”ASC Topic 926 Entertainment - FilmsASC专题926“娱乐业—电影”ASC Topic 928 Entertainment - MusicASC专题928“娱乐业—音乐”ASC Topic 930 Extractive Activities - MiningASC专题930...
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