ASB16-AS1目的探讨lncRNA ASB16-AS1在不同WHO分级胶质瘤标本中的表达量变化,以及在胶质瘤细胞系LN382U87MG中验证lncRNA ASB16-AS1对增殖、迁移、侵袭功能的影响。方法使用qRT-PCR技术检测lncRNA ASB16-AS1在临床肿瘤样本中表达量,分析lncRNA ASB16-AS1是否存在差异表达以及与肿瘤分期分级有无相关性。在LN382、...
Increased ASB16-AS1 was associated with the incidence of complications (P=0.033) and especially for pulmonary embolism in patients (P=0.029). ASB16-AS1 was negatively correlated with prothrombin time (PT,r= -0.763), antithrombin level (AT,r= -0.711), and international normalized ratio (INR,r...
Long non-coding RNAs (lncRNAs) have been proposed as therapeutic targets in CC. Hence, the present study evaluated the effect of ASB16-AS1 on CC via regulating miR-1305. 关键词: Long non-coding RNA ASB16-AS1 miR-1305 Cervical cancer Wnt/beta-catenin signal pathway 年份: 2020 ...
ASB16-AS1 was upregulated in GC samples according to GEO data and qRT-PCR analysis. ASB16-AS1 strengthened the proliferative ability and stem cell-like characteristics in GC cells. More importantly, ASB16-AS1 encouraged GC cell growth in vivo. Mechanistically, ASB16-AS1 strengthened TRIM37 ...
Real-time quantitative reverse transcription polymerase chain reaction ( qRT- PCR) was used to detect the expressions of ASB16-AS1 贾征王培山杨洋朱登彦王振华王伟Chinese Journal of Oncology
ASB16-AS1、miR-670-3p、ATXN7L3、胃癌、细胞增殖、迁移和侵袭背景多种长链非编码RNA(longnon-codingRNA,lncRNAs)在胃癌(gastriccancer,GC)进展中被证实发挥抑癌或促癌作用.但lncRNAs数量众多,仍有多种lncRNAs在GC进展中的作用并不明确.因此,筛选具有影响GC细胞增殖,迁移和侵袭的lnc RNAs对GC防治十分必要.目的探讨...
该文旨在探讨长链非编码RNA ASB16-AS1(LncRNA ASB16-AS1)靶向微小RNA-185-5p(miR-185-5p)/易位相关膜蛋白2(TRAM2)轴对口腔鳞状细胞癌(又称口腔鳞癌)细胞增殖,迁移和侵袭的影响.体外培养人口腔鳞癌细胞SCC-9,将其分为对照组,sh-NC组,sh-ASB16-AS1组,sh-ASB16-AS1+inhibitor NC组,sh-ASB16-AS1+miR-...
LncRNA ASB16-AS1 promotes proliferation and inhibits apoptosis of non small cell lung cancer cells by activating the Wnt/β catenin signaling pathwayTAN, L.-J.LIU, J.-T.YANG, M.JU, T.ZHANG, Y.-S.European Review for Medical & Pharmacological Sciences...
长链非编码RNA ASB16-AS1临床病理特征目的 探讨垂体腺瘤患者肿瘤组织中长链非编码RNA(lncRNA)ASB16-AS1表达水平与临床病理特征及预后的关系.方法 选取2015年8月-2017年8月于河南大学附属郑州颐和医院住院治疗的114例垂体腺瘤患者肿瘤组织作为垂体腺瘤组,选取各垂体腺瘤患者正常垂体组织作为对照组.采用实时荧光定量PCR(...
Hence, the present study evaluated the effect of ASB16-AS1 on CC via regulating miR-1305.Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapieLiu, WeiZhuang, RujinFeng, ShujunBai, XiaoxuJia, ZhaoyangKapora, ElenaTan, WenhuaHarbin Med Univ Affiliated Hosp 2 Dept Obstet &...