It is a monovalent lyophilized vaccine reconstituted with an adjuvant (AS01); both require cold chain storage [17]. Trial data showed the vaccine to be more efficacious and enabling protection against severe disease only when administered in a four dose schedule in children [2]. Mapping trial ...
In specific aspects, the immunization regimens involve the administration of a chimeric hemagglutinin (HA) and a liposomal adjuvant (e.g., ASOl) to a subject. Also provided herein are immunogenic/vaccine compositions for use in methods of immunizing or immunization regimens for human subjects ...