tenets of physician-driven pharmaceutical medicine, have flourished, seemingly arbitrarily, into the considerably broadened ambit of medicines development, with multiple scientific disciplines and professional backgrounds converging into the space, with the commensurate redefinition of desired knowledge, skills, ...
Schrodinger’s artificial intelligence (AI) powered software technology platform utilizes physics-based modeling and sophisticated machine learning algorithms to help clients identify the suitable molecules to treat the desired ailments. Its programs can help predict the behavior of molecules and potential ...
As an example, for drug delivery, nanomedicine aims to design and develop biocompatible nanoparticles (NPs) that can protect payloads from degradation and unwanted interactions with biosystems (e.g., immune cells and biological barriers) and deliver them to the desired biosystems (e.g., cells)3...
The calculations indicated that a minimum of 156 subjects will be required for each treatment arm, consid- ering the desired statistical power of 80%, the significance level of 10%, and the dropout rate of 10%. Therefore, a total of 312 subjects, equally stratified and randomized, will be ...
These proposed systems allow for microfluidic chips to be placed in a plethora of regions for comprehensive coverage of airborne virus collection in any desired setting. Optimization of the sampling flow rate and detection technique will emphasize either rapid detection or highly accurate quantification....
(NCC), and we will avoid such terms. Bacterial cellulose (BC) will also be used as a term, referring to the fibrillar material produced by the gram-negative bacteriaGlucanobacter xylinum. We will conform to the international organization for standardization (ISO) on the terminology used for ...
progression.2As hub proteins have also been linked to the progression of other chronic inflammatory diseases, further in-depth analysis and future investigations are desired. The co-occurrence of ferroptosis with periodontitis progression is a novel finding. The multi-dimensional analysis combining ...
Therefore, if a man decides to hold the door open but the approaching woman endorses the latter interpretation, that act of intended politeness will go awry and not have the desired effect.45 Alternatively, a man may decide not to hold the door open for a woman by appealing to the value...
Treatment with VPA will not be matter of dose-finding but a titration strategy will be applied in each patient looking for a serum concentration that is considered useful to produce the desired synergistic effect with radiotherapy and/or chemotherapy. Treatment will be administered orally starting at...
The term “therapeutically effective amounts” is meant to describe an amount of compound of the present invention effective in increasing the levels of serotonin, norepinephrine, or dopamine at the synapse and thus producing the desired therapeutic effect. Such amounts generally vary according to a...