To solve this problem, PNP-pincer type ligands19,37,38,39 were then considered because: (1) with a tridentate structure, they can form more stable complexes with the metal center in order to stabilize the intermediates in the catalytic cycle, and (2) by occupying only three coordination ...
In the anionic complexes 2 (Fig. 2b), the p-hole region represents a relative electron depletion and is positive at þ 25 kcal mol À 1 in the anionic species 2c. Next, we computed some complexes of 2 with electron rich partners and found that complexes [2c Á Á Á NCCH3]...
it is separately identified herein because of its particular utility as a preferred oil for use in the present emulsions. In addition, MCT oil is available commercially. Examples of such MCT oils include TCR (trade name of Societe Industrielle des Oleagineuax, France, for a mixture of triglycer...
The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes J. Comput. Aided Mol. Des., 11 (1997), pp. 425-445 View in ScopusGoogle Scholar Franzblau et al., 1998 S.G. Franzblau, R.S. Witzig, J.C. McLaughlin, P. Torres, G...
For example, some of them show interesting subtype selectivity on GABAAR complexes in vitro, results consistent with their in vivo effects. They can act as second-order modulators of first-order modulation by BZDs and modify the flumazenil-insensitive modulation of the GABAAR function [31]. Among...
To investigate the stability of the protein–ligand complexes described above, we have subjected these to molecular dynamics (MD) simulations without any constraints, allowing both the protein and the ligands to move freely. The Fe···N distance is an important parameter when considering if the ...
Marc FontecaveLaboratoire de Chimie et Biologie des Métaux; Université Joseph Fourier, CNRS UMR 5249, CEA, DSV/iRTSV/LCBM, Bâtiment K', 17 Rue des Martyrs, 38054 Grenoble Cedex 9, FranceJohn Wiley & Sons, Ltd.European Journal of Inorganic Chemistry...
Nos ingénieurs ont ainsi géré la livraison et supervisé la construction de projets de transport parmi les plus importants et les plus complexes au monde, que ce soit des projets de lignes à grande vitesse, de métro, de tramways, mais aussi de ferroviaire classique et de grands ouvrages...
Hazari, P.P., A.K. Pandey, S. Chaturvedi, A.K. Tiwari and S. Chandna (2012). Synthesis of oxovanadium(IV) Schiff base complexes derived from C-substituted diamines and pyridoxal-5-phosphate as antitumor agents, Chem. Biol. Drug Des., Vol. 79, No. 2, pp. 223-23...
(3-O-desacyl-4′-monophosphoryl lipid A) in combination with aluminum phosphate or hydroxide salts are used in the Cervarix VLP-based HPV vaccine to enhance the immune response in vaccine. In a recent study using filovirus VLPs as a model vaccine to evaluate several candidate vaccine adjuvant...