typically occurring as a multihit process with a point mutation in one allele and loss of the other wild-type (WT) allele1,2.TP53mutations are also strongly associated with copy number alterations (CNA) and structural variants, reflecting the role of p53 in the maintenance of genomic integrity...
The paper, published in February 2024 inEnvironmental Biology of Fishes, was originally titled “Expanded vertical niche for two species of pelagic sharks: depth range extension for the dusky sharkCarcharhinus obscurusand novel twilight zone occurrence by the silky sharkCarcharhinus falciformi.” ...
Intracellular pathogens are challenged with limited space and resources while replicating in a single host cell. Mechanisms for direct invasion of neighboring host cells have been discovered in cell culture, but we lack an understanding of how bacteria d
(2013). ‘Stem cell therapy without the cells’, Communicative & Integrative Biology, vol. 6, no. 6, p. e26631, Nov. https://doi.org/10.4161/cib.26631. Muthu, S., Bapat, A., Jain, R., Jeyaraman, N., & Jeyaraman, M. (2021). Exosomal therapy-a new frontier in regenerative ...
We have characterized a Ca 2+ current activated by depletion of intracellular Ca 2+ stores (capacitative Ca 2+ entry current) as a first step to investi... G.G. Schofield,M.J. Mason - 《Journal of Membrane Biology》 被引量: 30发表: 1996年 ...
Domain knowledge is essential: identifying the appropriate pharmacological endpoint, understanding its relevance to clinical efficacy, and defining the required intervention level demand deep understanding of disease biology and drug mechanism. Building translational models and conducting stochastic simulation to ...
SN Gangappa,S Berriri,SV Kumar - 《Current Biology Cb》 被引量: 18发表: 2017年 Brassinosteroid Biosynthesis Is Modulated via a Transcription Factor Cascade of COG1, PIF4, and PIF5 COG1 encodes a Dof-type transcription factor found previously to act as a negative regulator of the phytochrom...
The present paper aims at dealing with some issues of knowledge of the architectural heritage. Given the increasing use of the innovative technologies in the field of the cultural heritage it is important to focus on their usefulness and... A Aveta,BG Marino,R Amore - 《Isprs International Ar...
Thus, we demonstrate that paper and flexible material-based platforms can be widely applied to a variety of settings including medical diagnostic and biology laboratories. The combination of these sensing mechanisms on paper and flexible materials offers a promising opportunity to create diagnostic assays...
Bacterial extracellular vesicles: understanding biology promotes applications as nanopharmaceuticals. Adv. Drug Deliv. Rev. 173, 125–140 (2021). Ayers, L., Pink, R., Carter, D. R. F. & Nieuwland, R. Clinical requirements for extracellular vesicle assays. J. Extracell. Vesicles 8, 1593755 ...