A long-standing ecological assumption posits that insect herbivory increases in warmer, more stable climates at lower elevations. However, this paradigm ha
Programs that compare and align pairs of sequences, like ALIGN (E. Myers and W. Miller, "Optical Alignments in Linear Space", CABIOS (1988) 4: 11- 17), FASTA (W R. Pearson and DJ. Lipman (1988), "Improved tools for biological sequence analysis", PNAS 85:2444-2448, and W.R. ...
Download: Download high-res image (271KB) Download: Download full-size image Fig. 2. The process of autophagy. Under the amino acid or nutrient starvation conditions, the ULK1 complex (ULK1, Atg13, FIP200, and Atg101) gets activated by coordinated inputs from the mTORC1, which allows the...
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Download: Download high-res image (256KB) Download: Download full-size image Fig. 2. PREP inhibition induces CMA pathway activation and reduces the level of CMA substrate GAPDH in HEK-293 cells, and LAMP-2A siRNA restores the CMA pathway activation induced by PREP inhibition. HEK-293 wild-ty...
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The title compound was prepared by the method described in PCT application WO-99/24440. Example 148. MS: 361 (MH+); HPLC Rf: 5.37 min; HPLC purity: 98%. B. 2-(3-Methyl-3H-imidazol-4-yl)-7-(2-methyl-1H-indol-5-yloxy)-thieno[3,2-b]pyridine The title compound was prepared by...