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The crystal structure of the complex between the C-terminal fragment of CagA (885–1005 aa of H. pylori 26695 CagA) and PAR1 has shown that the CM motif mimics host substrates that bind to the kinase catalytic site of PAR1 [30]. In the crystals, the majority of the C-terminal ...
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Institutes of Health (NIH), Islamabad 44000, Pakistan 5 Director Vaccines Preventable Infectious Diseases, Chemonics International USAID Funded Global Health Supply Chain—Procurement and Supply, Management (GHSC-PSM) Project, Islamabad 44000, Pakistan * Correspondence: hashaam.ghsa@nih.edu.pk (H.A.)...