Aryl, alkyl, alkenyl and alkynyl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by oxidation and alkylation at C-4 of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune ...
Alkynyl‐, Aryl‐, and Alkenyl‐Substituted Benzo‐1,4‐quinonesorganic chemistry, reviewquinone derivativesChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or...
for solvolyses of tert-butyl chloride and of 4 show deviations from the ethanol/water correlation line (dispersion) in the order: aryl >> propargyl > allyl > alkyl; these trends are attributed to differences in solvation of the part of the alkyl group (R) adjacent to the reaction site. ...
摘要: The invention relates to 4-alkyl/4-alkenyl/4-alkynyl methyl/-1-arylcyclohexylamine derivatives, to a method for producing the same, to medicaments containing said compounds and to the use of 4-alkyl/4-alkenyl/4-alkynyl methyl/-1-arylcyclohexylamine derivatives for producing medicaments....
sulphur-containingtrans-platinum(ii) alkenylarylalkynyl complexes with general formulatrans-[(PR3)2–Pt–{CC–Ar–CHCH(SPh)}2], (where R = ethyl and Ar = phenylene2a, biphenylene2b, 2,5-dimethylphenylene2c, and 2,5-dimethoxyphenylene2d), having one phenylthio moiety in each alkenyl ...
aR=aryl, heterocyclyl, (cyclo)alkyl, (cyclo)alkenyl, alkynyl (all optionally substituted (os) by 1 or more T2), H, OH or alkylamino; R 1=group of formula (i); T=benzene ring or 5-6-membered heteroaryl; Z=N or CH; R 10=1-6C (halo)alkoxy, 1-6C alkylamino-1-6C alkoxy, ary...
All methods compiled before are not adequate for the preparation of bis(perfluoroorganyl)bromonium salts, [(RF)2Br]Y, where RF represent perfluorinated alkyl, alkenyl, alkynyl, and aryl groups. For example, the reaction of C6F5H with BrF3 in weakly coordinating solvents (CCl2FCClF2, 0 °C...
Chromium-Templated Synthesis of Densely Substituted Distorted Arenes − Intramolecular Benzannulation of [(Alkynylaryl)alkenyl]carbene Complexes to Plana... Chromium-Templated Synthesis of Densely Substituted Distorted Arenes − Intramolecular Benzannulation of [(Alkynylaryl)alkenyl]carbene Complexes to Planar...
85. A compound of formula A or B: wherein R4″ is selected from the group consisting of hydrogen and alkyl; R5 is selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted ...
(4) C2-15 alkynyl, (5) halo, (6) ORb, (7) aryl, or (8) heteroaryl, wherein said alkyl, alkenyl, alkynyl, and alkanoyl are optionally substituted with from 1-5 groups selected from Rc, and said aryl and heteroaryl optionally substituted with 1 to 5 groups selected from Rd ...