49. Lee SH,Harold D, Nyholt DR, et al. Estimation and partitioning of polygenic variationcaptured by common SNPs for Alzheimer’s disease, multiple sclerosis andendometriosis. Hum Mol Genet 2013;22:832-841. 50. Vi...
Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, in which the myelin sheaths got injured. The prevalence of MS is on grow, as well as, it affects the young ages. Females are most common to have MS compared to males. Oxida...
49. Lee SH,Harold D, Nyholt DR, et al. Estimation and partitioning of polygenic variationcaptured by common SNPs for Alzheimer’s disease, multiple sclerosis andendometriosis. Hum Mol Genet 2013;22:832-841. 50. Visscher PM,Wray NR, Zhang Q, et al. 10 Years of GWAS discovery: biology, ...
Currently used classification schemes for multiple sclerosis (MS) have not taken into account disease severity, instead focusing on disease phenotype (ie, relapsing vs. progressive). In this article, we argue that disease severity adds a crucial dimension to the clinical picture and may help guide...
Multiple sclerosis (MS) is a rare, intractable disease whose symptoms are caused by damage to the myelin sheath that surrounds the nerve fibers called axons that run throughout the body, including the brain, spinal cord, and optic nerves. When the myelin sheath is damaged, the axons are expo...
Correlation between MR and clinical findings of disease activity in multiple sclerosis. AJNR Am J Neuroradiol 1999; 20:1777–1778. CAS PubMed PubMed Central Google Scholar Raine CS, Scheinberg LC . On the immunopathology of plaque development and repair in multiple sclerosis. J Neuroimmunol 1988...
Summary: Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system that often leads to disability in young adults. Treatmen... PA Gourraud,HF Harbo,SL Hauser,... - 《Immunological Reviews》 被引量: 334发表: 2012年 What role for genetics in the prediction of...
sclerosis, Sj枚gren syndrome and multiple sclerosis) was 1.4% in older women (95% CI: 1.3%, 1.5%) with significant variation across regions of the ... Mary,M A.,Rogers,... - 《Journal of Autoimmunity》 被引量: 27发表: 2012年 Celiac disease with cerebral and peripheral nerve involvement...
The increasing search for the causes of multiple sclerosis has led in the past two decades to a close reexamination of the old idea that constitutional or genetic factors may play some role in the etiology of this disease. The evidence currently presented for or against a hereditary background...
Myelin, the membrane surrounding neuronal axons, is critical for central nervous system (CNS) function. Injury to myelin-forming oligodendrocytes (OL) in chronic neurological diseases (e.g. multiple sclerosis) ranges from sublethal to lethal, leading to