Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome. Sci Immunol. 2020;5. https://doi.org/10.1126/sciimmunol.aax7969. Lu C, Guo C, Chen H, Zhang H, Zhi L, Lv T, et al. A novel chimeric PD1-NKG2D-41BB receptor enhances antitumor activity of...
γδ T cells form an important part of adaptive immune responses against infections and malignant transformation. The molecular targets of human γδ T cell receptors (TCRs) remain largely unknown, but recent studies have confirmed the recognition of pho
Google Share on Facebook Polybenzimidazole Acronyms The following article is fromThe Great Soviet Encyclopedia(1979). It might be outdated or ideologically biased. a polymer containing benzimidazole rings in the main macromolecular chain: where R = H, C6H5, or an alkyl. ...
At present, research and development of novel vaccine adjuvants are mainly focused on TLR ligands. Targeting TLR signaling pathways has been applied in clinical practice to improve the immunogenicity of DNA vaccines and promote the adjustment of T cells in resisting viral infection or to inhibit the...
This study was carried out to determine the effect of recombinant human bone morphogenetic protein (rhBMP) pharmacokinetics (PK) on rhBMP-induced osteoindu... H Uludag,D D'Augusta,J Golden,... - 《Journal of Biomedical Materials Research》 被引量: 0发表: 2000年 Error Rate Performance of MC...
Prangemeier, T.; Reich, C.; Koeppl, H. Attention-Based Transformers for Instance Segmentation of Cells in Microstructures. In Proceedings of the 2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Seoul, Korea, 16–19 December 2020; pp. 700–707. [Google Scholar] Nation...
2024年3月11日,中山大学张辉及广州实验室马显才共同通讯在Molecular Cancer(IF=37)在线发表题为“The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments”的研究论文,该研究构建了一种新型模块化通用CAR-T ...
引言: 嵌合抗原受体T细胞疗法(CAR-T)是近年来发展非常迅速的一种新型细胞免疫治疗技术,CAR-T免疫疗法是通过给T细胞装备能识别特定肿瘤细胞的分子,在识别肿瘤细胞后能引起T细胞的激活和增殖,从而可以有效杀伤肿瘤细胞。2017年,FDA批准两个CAR-T产品上市,一个是诺...
Mobile Videophones May Finally Arrive on Scene SAN FRANCISCO -- Back in the `50s, visionaries knew what the `90s would be like.People would rocket to work using a personal jet pack, or maybe glide in a luxurious hovercar. At home, robots would tend to their domestic needs. When Mom c...
These data confirmed the apoptotic action of YK on ovarian cancer cell line. Figure 1 Growth inhibitory effect of YK on different cell lines. A. HEK293T, A549, HepG2, Hela, IHH and SKOV6 cells were treated with different doses of YK (1, 10, 100 μg/ml) and analyzed for cell ...