Article 2的定义部分不仅仅是基础术语，更体现了MDR法规的核心监管方向：加强临床数据要求：制造商不能仅依赖现有文献，必须提供高质量的临床证据。强化软件监管：SaMD、AI医疗软件等需符合MDR要求，避免“擦边球”产品规避监管。提升供应链责任：进口商、分销商需主动核查产品合规性，确保市场上流通的器械安全有效。可...
Repositorio que contiene los archivos y scripts del artículo "Maternal transmission of bacterial microbiota during embryonic development in a viviparous lizard", del laboratorio de Interacciones Bióticas, Tlaxcala, México. - Article-Transfer/PCA-suppl
Short-term exposure (30 min) of cells (~107 cells/mL) to PMB was conducted using anaerobic MIC (4 µg/mL) with E. faecium KACC 11954 and MDR E. faecium D2–132 in R2A liquid (Figure 1d, 1e). The cell densities of both E. faecium strains grown aerobically remained stable,...
https://media.defense.gov/2022/Oct/27/2003103845/-1/-1/1/2022-NATIONAL-DEFENSE-STRATEGY-NPR-MDR.PDF(open in a new window). (Open in a new window)Google Scholar US Department of Defense. 2022b. “Military Construction Program: FY2024 Budget, North Atlantic Treaty Organization Security ...
The hepatic P450 cytochrome CYP3A4 enzyme metabolizes colchicine, and the P-glycoprotein (P-gp; also known as multidrug resistance protein-1; MDR1) efflux pump in the liver and kidneys removes it. The MDR1 gene, encoding P-gp, and specific MDR1 polymorphisms have been associated with ...
Abstracts of the Federation of Infection Societies (FIS) Annual Conference and the 10th Healthcare Infection Society (HIS) International Conference 2016 Last update November 2016 Prevention and control of multi-drug resistant (MDR) Gram-negative bacteria: recommendations from a Joint Working Party ...
The majority of these drugs, which are administered systemically, are non-selective and therefore also target healthy cells3. Moreover, during treatment cancer cells often develop multidrug resistance (MDR) phenotypes, such as enhanced drug efflux, activation of nuclear DNA repair mechanisms and ...
The epizootiology, epidemiology, and pathogenesis of pseudotuberculosis have not been adequately studied. Under natural conditions, infection occurs through the alimentary canal, respiratory tract, and injured skin. The main sources of the pathogen are sick and convalescent animals and contaminated feed and...
[32]. The sensitivity and specificity of the 2 quantitative parameters, MDRAI/GI (the maximal diameter ratio of the lesion in contrast-enhanced ultrasound images [CI] and that in gray-scale images [GI]) and ARAI/GI (the area ratio of the lesion in CI and that in GI), based on At-...
of infections, the majority of which were caused by Multi Drug Resistant Gram Negative Bacilli (MDRGNB), followed by Candida species and Cryptococcus species, Methicillin Resistant Staphylococcus aureus (MRSA), and Mycobacterium tuberculosis... R Ravikumar,K. JyothiE.,B. Dutta,... - 《Journal of...