However, the major drawback of PVR is that the waveforms are subjectively evaluated by each observer, thus making it difficult to obtain reliable results unless the observer has sufficient experience and skill. In the present study, ABI, %MAP and UT were automatically measured and calculated with...
PVR: Pulmonary vascular resistance MM: Module membership GS: Gene significance PCs: Principal components RT-qPCR: Real-time quantitative PCR UMAP: Uniform Manifold Approximation and Projection GZMA: Granzyme A GZMK: Granzyme K CCL5: C-C Motif Chemokine Ligand-5 CXCL9: C-X-C Motif...
predicted smoking status, first ten principal components computed from control probes and the first five “epi-structure” principal components to adjust for batch and ancestry differences. In this study, CpG markers reaching an epigenome-wide threshold (p < 10−7) after adjustment for the g...
A vasodilator response was defined as a fall in PVR of 30% or more. Both drugs produced similar vasodilator response (37% were responders to both medications).29 A retrospective study by Sitbon et al. showed that in patients who have a positive vasodilator response, the mPAP change was ...
In our study, the differences in clinical parameters in all patients as a single group were not similar to the differences in subgroup patients. Event women had significantly higher PVR and lower CO compared with event-free women, which indicates that event women had a more severe clinical ...
The funding body had no influence on the design of the study and collection, analysis, and interpretation of data and writing of the manuscript. Author information Authors and Affiliations Department of Internal Medicine II, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, ...
In the present study, inhibition of Shp2 effectively reduced increases of PAMT and perivascular fibrosis in PAH rat lungs. Moreover, Shp2 inhibition ameliorated pulmonary arterioles muscularization in rats. Therefore, inhibition of Shp2 effectively inhibited PVR in MCT-induced PAH rats. Myocardial ...
Role of the Funder/Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. ...
An abnormal upper-thigh PVR waveform with a normal triphasic common femoral Doppler waveform indicates proximal superficial femoral artery disease, whereas an abnormal upper-thigh PVR waveform with an abnormal common femoral Doppler waveform indicates aortoiliac disease. Errors in interpretation can ...
eGFR, estimating glomerular filtration rate; MDRD, Modification of Diet in Renal Disease; mPAP, mean pulmonary artery pressure; PVR, pulmonary vascular resistance; SV, strove volume. Source data Extended Data Fig. 6 Information of NT-proBNP in the UK and the combined cohort. (A) In the UK...