Assessment of arterially hyper-enhancing liver lesions using virtual monoenergetic images from spectral detector CT: phantom and patient experienceSpectral detector computed tomographyImage qualityVirtual monoenergetic imagesHyper-attenuating liver lesions
Predictive models were developed using logistic regression (LR), random forest (RF), and eXtreme Gradient Boosting (XGBoost), with particle swarm optimization (PSO) used to optimize their hyperparameters. The SHapley Additive exPlanation (SHAP) method was applied to determine the importance of risk ...
Over the years, mounting evidence has explored the role of dysregulated miRNAs in the hyperproliferative and apoptosis-resistant phenotype of pulmonary vascular cells, including PAECs, PASMCs, and PAAFs, in the different PH rodent models and human PAH tissues. Because of the exhaustive list of suc...
This smooth muscle cell (SMC) hyperproliferation causes an increase in pulmonary arterial diameter, that consequently increases the pulmonary vascular pressure due to blood flow resistance (Tuder et al., 2001, Archer et al., 2010). Many signalling pathways (e.g., nitric oxide (NO) pathway, ...
The progression of pulmonary arterial remodeling is through increased proliferation and resistance to apoptosis of ECs and SMCs. In particular, hyperproliferation of ECs can result in a clustered appearance resulting in the formation of complex plexiform lesions [29], occlusion of the blood vessel, an...
One hundred seventeen HCC nodules (91.4%) were hyperenhancing in the arterial phase on the preoperative imaging studies. The percentage of tumor necrosis was greater than 90% in 48 nodules (38%), between 50% and 90% in 19 nodules (15%), and less than 50% in 61 nodules (48%); tumor...
Malignant focal liver lesions displaying rim arterial phase hyperenhancement may have a vascular, hepatocellular, biliary, lymphoid, or secondary origin. The differences in imaging characteristics on contrast-enhanced CT may be subtle, and a multiparametric approach on MRI may be helpful to narrow the...
Virtual monoenergetic images from spectral detector computed tomography facilitate washout assessment in arterially hyper-enhancing liver lesionsCarcinoma, hepatocellularTomography, X-ray computedDiagnostic imagingImage quality and quantitative washout parameters as well as subjective washout visibility and diagnostic...
All lesions (5鈥 20mm) showed arterial hyperenhancement with isoattenuation on portal venous phase or delayed phase without typical features of AP shunt. We evaluated and analyzed the attenuation of the lesions with qualitative and quantitative methods in each phase. The size, location, shape, ...
Three 16 cm axial liver acquisitions were obtained during a single breath hold at peak aortic enhancement plus 10, 20, and 25 s. Two readers working separately scored overall exam quality, identified hyperenhancing lesions, and subjectively scored and ranked relative lesion conspicuity. Objective ...