art是一个英文单词，全称为antiretroviral therapy，中文译为抗逆转录病毒治疗。它是一种针对人类免疫缺陷病毒（HIV）感染的治疗手段。art病例是指接受了art治疗的HIV感染患者。art治疗的原理是通过使用不同种类和不同作用机制的药物，共同抑制HIV病毒在体内的复制和繁殖，从而达到减少体内病毒负载，保持或恢复...
Interruption of combination antiretroviral therapy (ART) in HIV-1-infected individuals leads to rapid viral rebound. Here we report the results of a phase IIa open label clinical trial evaluating 3BNC117, a broad and potent neutralizing antibody (bNAb) against the CD4 binding site of HIV-1 Env...
HIV感染者的神经系统并发症可由HIV本身引起,也可继发于机会性感染(opportunistic infection, OI)[1]。 在抗逆转录病毒治疗(antiretroviral therapy, ART)广泛应用前,患者免疫功能逐步下降,最常见的中枢神经系统(central nervous system, CNS)并发症是由...
参考文献:Benlarbi M, Richard J, Bourassa C, et al. Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals Wit...
The use of ART in HIV treatment has resulted in increased patient longevity and drug toxicity. The aim of this study was to devise a method for quantifying patient medications. We introduced the concept of a medication (reed) score that represents the ratio of amount of medication taken to ...
近日, 美国约翰霍普金斯大学医学院的一个研究团队发布了一篇文章,这篇文章主要探讨了即使在进行了数十年的抗逆转录病毒治疗后,患者体内可诱导、可感染的HIV-1的潜伏储备并没有减少的现象。这一发现对于HIV治疗和研究具有重要意义,因为它强调了消除HIV潜伏储备的挑战性。而在此前(2003年),该团队曾根据HIV共存者启动...
[3] Phillips A N, Stover J, Cambiano V, et al. Impact of HIV drug resistance on HIV/AIDS-associated mortality, new infections, and antiretroviral therapy program costs in sub–Saharan Africa[J]. The Journal of infectious diseases, 2017, 215(9): 1362-1365. ...
[3]Gandhi M, Hickey M, Imbert E, et al. Demonstration Project of Long–Acting Antiretroviral Therapy in a Diverse Population of People With HIV. Ann Intern Med. 2023;176(7):969–974. doi:10.7326/M23–0788 来源:《感染医线》 声明 ...
non-pharmacologic therapySymptom management for persons living with HIV/AIDS is an extremely important component of care management. The importance of pharmacologic interventions for management of symptoms is well recognized, and non-pharmacologic strategies such as art therapy are gaining interest in lay...
Objectives The aim of our study was to identify symptom clusters and to examine demographic and health-related factors associated with these symptom clusters among PLWH prescribing antiretroviral therapy (ART) in China.MethodsFrom April to September 2017, we recruited 1116 participants through a convenie...