(in addition to very new approaches, see Sect.7.2) being used to produce peptide arrays: in situ parallel on-chip synthesis or immobilization of presynthesized peptides on the array surface. Each has its own advantages and shortcomings. Hence, the choice of the approach for peptide array ...
A composition including (a) a solid support having a surface; (b) a first plurality of nucleic acids immobilized on the surface, wherein the nucleic acids in the first plurality each include the P7 primer sequence (5′-CAAGCAGAAGACGGCATACGA-3′; SEQ ID NO: 3); and (c) a second plu...
the viability of organoids (green: live cells; red: dead cells). Scale bar, 200 µm. The experiments are repeated three times.g,hComparison of the growth rates (g) and the viabilities (h) in four organoid lines indicating no significant difference between the LCOs cultured on-chip ...
Thus, this process, a mainstay of biological labs for decades, must be repeated several times to isolate pure clonal cell populations, a laborious and time-consuming process. More efficient, less labor and time intensive, cloning methods would be of significant benefit across a wide range of ...
This is repeated for the lower left hole 23 of the upper right corner sub grid and finally the lower left hole 24 of the upper left corner sub grid. As shown in FIG. 12, the four points 1201-1204 (found in this example at the extreme corners of the chip) are used to calculate ...
Typically, CCD arrays have no external reference to locate the photosites within the package. Thus, the usual practice is to use a microscope to locate the photosites and then position the entire package within some sort of holder. Alternatively, once the CCD array has been mounted on a circ...
A method for synthesizing and screening oligonucleotides on a solid substrate. The method provides for the irradiation of a first predefined region of a substrate comprising immobilized nucleotides on its surface, without irradiation of a second predefined region of the substrate. The irradiation step ...
In addition, the cost-effectiveness of infectious disease diagnosis by nucleic acid analysis varies directly with the multiplex scale in panel testing. Many of these applications depend on the discrimination of single-base differences at a multiplicity of sometimes closely space loci. A variety of ...