Despite continued cost reduction in raw base generation, improvement in base-calling accuracy, andrecent advances in read length, complete de novo assembly with accurate genome wide structuralvariant (SV) analysis of an individual large complex genome remains expensive and challenging. Inparticular, ...
c Reconstructed data using the localized rank-reduction method Full size image We apply the two rank-reduction methods to the preprocessed data. Figure 8b shows the reconstructed data using the global rank-reduction method. In global reconstruction, we treat the whole 3D data cube as the input ...
Seismic arrays, first introduced in the late 1950s to detect underground nuclear explosions, have helped to improve our knowledge about the structure of the Earth for the last 40 years. During these years, numerous array processing methods have been developed that use the high signal coherence and...
Laubenbacher R, Hower V, Jarrah A, Torti SV, Shulaev V, Mendes P, Torti FM, Akman S: A systems biology view of cancer. Biochim Biophys Acta 2009, 129–139. Google Scholar Thorgeirsson SS, Grisham JW: Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002, 31: 339–...
The hard clam (Mercenaria mercenaria), a marine bivalve distributed along the U.S. eastern seaboard, supports a significant shellfish industry. Overharvest in the 1970s and 1980s led to a reduction in landings. While the transition of industry from wild
Methods Preparation of VFACs. To prepare the VFAC, a 1-mm square chip with an array of microchambers was fab- ricated by the injection molding (Fluidware Technologies, Inc. (Kasukabe-shi, Saitama-ken, Japan) of polydimeth- ylpolysiloxane (PDMS). In the array, 75-μm diameter ...
Methods Preparation of VFACs. To prepare the VFAC, a 1-mm square chip with an array of microchambers was fab- ricated by the injection molding (Fluidware Technologies, Inc. (Kasukabe-shi, Saitama-ken, Japan) of polydimeth- ylpolysiloxane (PDMS). In the array, 75-μm diameter ...
Methods Case selection For the past two years, of the 2509 cases analyzed by karyotyping and MLPA, numerical chromosomal and structural abnormalities were noted in 106 (4.2%) and 102 cases (4.1%), respectively. Of cases with structural chromosomal abnormalities detected by karyotyping, suspected gen...
Since elevation of intracellular calcium is part of the process which leads to cell damage, reduction in calcium entry would decrease neural damage in cerebral ischemia. SUMMARY OF THE INVENTIONThe present invention is directed to an isolated and purified DNA molecule which encodes a β subunit ...
because it excludes the use of electroosmotic flow in sample transport. Pressure driven flow has been the other popular method used for sample transportation in previous ESI chips. However, both of these methods require an external actuator, such as a high-voltage supply or a pump. Pressure driv...