Synonyms Array-based comparative genomic hybridization Definition Array-based comparative genomic hybridization (array CGH) is a technique to assay the genome for identifying chromosomal segments with copy number alterations. This technique utilizes printed microarrays ( Microarray (cDNA) technology ) to ...
Array based comparative genomic hybridization (array CGH) has emerged as a powerful tool for detecting gene copy number variants implicated in many disease states. Simple, robust genomic DNA labeling reagents and removal of free dye and nucleotides are two of the most critical components dete...
作为疾病的一项生物标 志,染色体水平的缺失、扩增等变化已成为许多疾病研究的热点,然 而传统的方法(比如G显带,FISH, CGH等)存在操作繁琐,分辨率 低等问题,难以提供变异区段的具体信息。 基于芯片技术的比较基因组杂交(aCGH:array-based Comparative Genomic Hybridization)平台解决了上述问题。通过 在一张芯片上用标记...
Array-Based CGH for Genomic DNA Analysis - ULS Labeling 7 1 Before You Begin Procedural Notes Procedural Notes • To process SurePrint G3 CGH+SNP microarrays, refer to the Agilent Oligonucleotide Array-Based CGH for Genomic DNA Analysis (Enzymatic Labeling for Blood, Cells, or Tissues) ...
Array-based CGH is a high-throughput technique to measure DNA copy number change across the genome. The DNA fragments or "clones" of test and reference samples are hybridized to mapped array fragments. Log2 intensity ratios of test to reference provide useful information about genome-wi...
Agilent Oligonucleotide Array-Based CGH for Genomic …:安捷伦寡核苷酸微阵列CGH基因组… 热度: CGH40010 10 W射频功率GaN HEMT-CGH40010 热度: 2008 CGH Basic Introduction_Zemax II 热度: Fax+41613061234 E-Mailkarger@karger.ch .karger HumanCytogeneticsCaseReport ...
目的 探讨无创产前检测技术(noninvasive prenatal testing,NIPT)联合基于微阵列芯片的比较基因杂交技术(array-based comparative genomic hybridization,Array-CGH)在染色体微缺失或重复中的产前检测价值.方法 选择孕12～24周高危孕妇,采集静脉血并提取循环胎儿游离DNA(cell-free fetal DNA,cffDNA),利用NIPT技术检测,结果为...
Array-based comparative genomic hybridization (array CGH) is a technique to assay the genome for identifying chromosomal segments with copy number alterations. This technique utilizes printed microarrays (Microarray (cDNA) technology) to perform a simultaneous analysis of selected genomic regions or even ...
In recent years, CGH method using custom-designed high-density oligonucleotide-based arrays allowed the development of a powerful tool for detection of alterations at the level of exons and made it possible to provide flexibility through the possibility of modeling chips. The aim of our study was...
Targeted aCGH arrays are based on our patented ab initio technology (US Patents7,734,424,8,209,129, and8,407,013).