Cytosolic Aminotransferase VAS1 Coordinates Aromatic Amino Acid Biosynthesis and Metabolism Aromatic amino acids (AAAs) play a crucial role in the synthesis of proteins across all living cells as well as in the generation of various pri...
Aromatic amino acidsBranched-chain amino acidsMediterranean dietType 2 diabetesAIMS/HYPOTHESIS: Branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) are associated with type 2 diabetes. However, repeated measurements of BCAA/AAA and their interactions with dietary interventions have not ...
BACKGROUNDObesity and insulin resistance are linked with mood disorders, and elevated concentrations of branched-chain (BCAAs) and aromatic amino acids (AAAs). Our study aimed to prospectively assess the relationship between childhood plasma BCAAs and AAAs and behavioral problems in young Inuit from ...
Diabetic nephropathyAromatic amino acidsPhenylalanineTryptophanTyrosineBackground We aimed to estimate the associations between aromatic amino acids (AAAs) and diabetic nephropathy (DN) in patients with type 2 diabetes (T2D). Methods We collected clinical and metabolomic data from 132 healthy subjects (HS...
L-tryptophan, L-phenylalanine, and L-tyrosine are aromatic amino acids (AAAs) that are used for the synthesis of proteins and that in plants also serve as precursors of numerous natural products, such as pigments, alkaloids, hormones, and cell wall components. All three AAAs are derived from...
Aromatic aminotransferases (Aro ATs) are pyridoxal-5-phosphate (PLP)-dependent enzymes that catalyze the transamination reactions of anaromatic amino acid(AAA) or a keto acid. Aro ATs are involved in biosynthesis or degradation of AAAs and play important functions in controlling the production of ...
(CHA), which is the end product of shikimate pathway and the starting precursor for the synthesis of aromatic amino acids (AAAs) [48,49]. The first step for the synthesis of ʟ-tyrosine (ʟ-Tyr) and ʟ-phenylalanine (ʟ-Phe) is catalyzed by chorismate mutase (CM), which is ...
Glyphosate inhibits the shikimic pathway of the synthesis aromatic amino acids (AAAs), phenylalanine, tyrosine and tryptophan. Greenhouse experiment was conducted using infested pots with O. crenata to explore the possibility of co-exposure AAAs with glyphosate to alleviate glyphosate effects on faba ...
L-tryptophan, L-phenylalanine, and L-tyrosine are aromatic amino acids (AAAs) that are used for the synthesis of proteins and that in plants also serve as precursors of numerous natural products, such as pigments, alkaloids, hormones, and cell wall components. All three AAAs...
AAAs are less abundant than other amino acids inside the cell; moreover, the flux toward their biosynthesis is highly regulated. In particular, the availability of E4P is severely limited in many microorganisms12,17–19, resulting in a significant constraint on entry flux for AAA biosynthesis. ...