The A2B AR has been shown to mediate adenosine-induced anti-platelet function, but its effect has not been shown in human [3]. The antiplatelet effects of the A1 and A3 AR have not been clearly defined, especially in humans. Earlier studies have demonstrated that adenosine activates adenylyl ...
Plant peroxidases (class III peroxidases) are present in all land plants. They are members of a large multigenic family. Probably due to this high number of isoforms, and to a very heterogeneous regulation of their expression, plant peroxidases are involved in a broad range of physiological proce...
These latter studies imply that R-loops might be involved in organizing local chromatin structures which might contribute to the regulation of ATM/ATR kinase activity. Thus, understanding how centromeric chromatin conformation contributes to both centromere organization and centromere maintenance is an ...
GPCR-mediated signaling alters a variety of cellular events, including cell adhesion and migration, mitosis, the regulation of gene expression, and cell–cell communication [11]. As cell surface signaling proteins with a range of different functions, GPCRs are attractive drug targets. Thus, it is...