(2000) Ethical and scientific challenges of placebo control arms in clinical trials. International Journal of Pharmaceutical Medicine 14 , 149-157 /De Deyn PP. Ethical and scientific challenges of pla- cebo control arms in clinical trials. International Journal of Pharmaceutical Medicine. 2000;14:...
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Conclusion and RelevanceThis crossover randomized clinical trial showed that commonly used arm positions (lap or side) resulted in substantial overestimation of BP readings and may lead to misdiagnosis and overestimation of hypertension. Trial RegistrationClinicalTrials.gov Identifier:NC...
Now we know how to use these methods, let’s address why you should. Synthetic control arms offer several significant benefits in clinical trials, making them an increasingly popular option in modern research. Some of the key reasons to choose this method include: Increasedpatient participation:You...
We systematically searched PubMed, Embase, and Cochrane Library up to February 2022 for randomized clinical trials (RCTs) that analyzed the occurrence of subsequent fractures in untreated patients with prior VFFs. Two authors independently extracted data and appraised the risk of bias in the selected...
expensive, and uncertain process of clinical drug development, including potential delays in or failure to obtain regulatory approvals; our reliance on third parties and collaborators to conduct our clinical trials, manufacture our product candidates, and develop and commercialize our pro...
According to a federal clinical trials database, a Phase III study for elritercept in MDS is set to begin by the end of the year. “Following the recent partnership for elritercept with Takeda, the PAH program was [Keros’] lead program and also where majority of the...
Some of those therapists have experi- ence as study administrators in a prior randomized controlled trial for GAD (ClinicalTrials.gov Identifier: NCT02039193). All therapists will participate in an initial 16-h workshop presented by one of the co-developers of the treatment manual (Zinbarg) [...
Randomized phase II clinical trials. Randomized Phase II trials entering patients prospectively to both experimental and control arms have been proposed to avoid any bias in such cases. The ... SH Jung,DJ Sargent - 《Journal of Biopharmaceutical Statistics》 被引量: 90发表: 2014年 S3-1: Update...
MicroPort®Honghu has demonstrated its technical advantages such as accurate operation, efficient collaboration, safety protection and high compatibility in the clinical trials. Its planning system can help surgeons make personalized implant plans before the procedure on the basis of pre-operative CT scan...