#小普日报每天阅读一分钟,行业热点全知道☆ 关键词瑞戈非尼 纳武利尤单抗 米吉珠单抗 司库奇尤单抗 阿达木单抗 1型糖尿病 Mpox 纳鲁索拜单抗 珂罗利单抗 今日行业热点#①The Lancet Oncology:First-line regorafenib with nivolumab and chemotherapy in advanced oesophageal, gastric, or gastro-oesophageal junction ...
3. In research on a therapeutic agent, one of several possible interventions. Most clinical trials include an active treatment arm – in which participants are exposed to the agent that is under study – as well as a placebo arm – that is, a sham therapy used for the purpose of contrast...
A sequence of epochs (time intervals) during which treatment is consistent, defining the course of a subject’s participation in a trial. Trials The “side” on which a patient in a controlled clinical trial is placed, which is usually either a treatment/experimental arm, or a placebo/control...
The average duration of exposure was 82 days in the fluticasone propionate MDPI groups compared with 75 days in the placebo group. Table 1 displays the incidence of most common adverse reactions in pooled Trials 1 and 2. Table 1: Adverse Reactions with ≥ 3% Incidence with Fluticasone ...
We discuss group-sequential three-arm noninferiority clinical trial designs that include active and placebo controls for evaluating both assay sensitivity and noninferiority. We extend two existing approaches, the fixed margin and fraction approaches, into a group-sequential setting with two decision-...
First-line serplulimab or placebo plus chemotherapy in PD-L1-positive esophageal squamous cell carcinoma: a randomized, double-blind phase 3 trial Article Open access 02 February 2023 Introduction Esophageal cancer is associated with significant mortality, particularly in Asia, where esophageal squamous...
Ryan CJ, Smith MR, Fizazi K, Saad F, Mulders PF, Sternberg CN et al (2015) Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-bli...
In this multi-center phase II trial, we evaluated the efficacy and safety of a quadruplet regimen (pembrolizumab, trastuzumab, and doublet chemotherapy) as first-line therapy for unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-
Other inclusion criteria were an Eastern Cooperative Oncology Group (ECOG) performance status of 0–1 and adequate organ function. Before treatment initiation, mandatory chest and abdomen computed tomography (CT) scans, brain magnetic resonance imaging (MRI) or CT scans, and positron emission ...
aFail to create AVS file 不要创造AVS文件 [translate] aaverage baseline Masood score was 13.5 with a mean decrease of 0.46+-2.5points in the placebo group 平均基础线Masood比分是13.5以0.46+-2.5points卑鄙减退在安慰剂小组 [translate] a琳达考虑这周末去看望她 Linda considered this weekend sees her...