Hirose, I. Nakase, Arginine-rich peptides: methods of translocation through biological membranes, Curr. Pharm. Des. 19 (2013) 2863-2868.Futaki S, Hirose H, Nakase I. (2013). Arginine-rich peptides: methods of translocation through biological membranes. Curr Pharm Des 19: 2863-8....
The translocation of hexa-arginine peptides across the asymmetric lipid bilayer in both random and bundled state was studied by coarse-grained molecular dynamics simulations. It was found that the peptides pass through the membrane by a pore-mediated mechanism when their concentration exceeds a ...
Figure 1. Structure of arginine-rich peptides used in this study. C-terminal cysteine amide (C*) was fluorescein-labeled for monitoring the internalization of the peptides by fluorescence microscopy. d-Amino acids are denoted initalics. Cysteine residues corresponding to positions 154 and 269 in ...
Foldamers, which are folded oligomers with well-defined conformations, have been recently reported to have a good cell-penetrating ability. α,α-Disubstituted α-amino acids are one such promising tool for the design of peptide foldamers. Here, we prepared four types of L-arginine-rich ...
This is not to say all cell-penetrating peptides behave in the exact same manner, nor do they exhibit identical activity profiles. Rather we propose that the structure function relationships observed in the TAT peptide may apply to similarly structured arginine-rich peptides. 2. TAT as a proto...
Recently, the polycationic peptide dfTAT was identified as a reagent that induces the efficient leakage of late endosomes and, thereby, enhances the penetration of macromolecules into the cytosol of live human cells. To gain further insights into the features that lead to this activity, the role ...
Arginine-rich Peptide Coated PLGA Nanoparticles Enhance Polymeric Delivery of Antisense HIF1α-oligonucleotide to Fully Differentiated Stiff Adipocytes. Toxicol. Environ. Health Sci. 11, 1–10 (2019). https://doi.org/10.1007/s13530-019-0382-8 Download citation Received03 September 2018 Revised16 ...
求翻译:Tryptophan- and arginine-rich antimicrobial peptides:是什么意思?待解决 悬赏分:1 - 离问题结束还有 Tryptophan- and arginine-rich antimicrobial peptides:问题补充:匿名 2013-05-23 12:21:38 色氨酸和精氨酸丰富的抗菌肽: 匿名 2013-05-23 12:23:18 色氨酸和酸丰富抗菌多肽: 匿名 ...
Cell-penetrating peptides are widely used as molecular transporters for the internalization inside cells of various cargo, including proteins and nucleic acids. A special role is played by arginine-rich peptides and oligoarginines covalently linked or simply mixed with the cargo. Here we report cell...
Wan Z,Lu S,Zhao D,et al.Arginine-rich ionic complementary peptides as potential drug carriers:Impact of peptide sequence on size,shape and cell specificity[J].Nanomedicine:Nanotechnology,Biology and Medicine,2016,12(6):1479-1488.Z. Wan, S. Lu, D. Zhao, Y. Ding, P. Chen, Arginine-...