Researchers: Brain activity, anorexia connected; Increased activity is found in area of the brain that controls reward and reinforcementASSOCIATED PRESS
The medial preoptic area (mPOA) differs between males and females in nearly all species examined to date, including humans. Here, using fiber photometry recordings of Ca2+ transients in freely behaving mice, we show ramping activities in the mPOA that pr
Dopamine signaling in the amygdala is known to play a role in associative learning and memory, including the process of learning to associate environmental cues with the reinforcing properties of drugs like cocaine. Evidence suggests that the ventral tegmental area (VTA) dopamine (DA) projection spec...
The anterior portion of the hypothalamus also contains the suprachiasmatic nucleus (SCN), which is the circadian pacemaker. Via its projections to other hypothalamic nuclei, the SCN provides circadian influences on the sleep–wake cycle, body temperature, hormone secretion, and other biological rhythms...
et al. Functional, anatomical, and neurochemical differentiation of medial preoptic area subregions in relation to maternal behavior in the mouse. J. Comp. Neurol. 521, 1633–1663 (2013). CAS PubMed Google Scholar Zhao, Z. D. et al. A hypothalamic circuit that controls body temperature. ...
Brain Structure and Function (2022) 227:1083–1098 https://doi.org/10.1007/s00429-021-02449-8 ORIGINAL ARTICLE Characterization of orexin input to dopamine neurons of the ventral tegmental area projecting to the medial prefrontal cortex and shell of nucleus accumbens Imre ...
Lesioned rats are unable to concentrate their urine as well as controls. In addition, lesioned rats overdrink in response to 24-h water deprivation. This lesion also causes a natriuresis and an overconsumption of 3% NaCl solution. These findings establish the AP-cmNTS as an important part ...
The activation of GABAB receptors in the ventral tegmental area (VTA) has been suggested to attenuate the rewarding properties of psychostimulants, including nicotine. However, the neurochemical mechanism that underlie this effect remains unknown. Since
Dysregulation of brain homeostasis is associated with neuropsychiatric conditions such as major depressive disorder. However, underlying neural-circuit mechanisms remain not well-understood. We show in mice that chronic restraint stress (CRS) and social
To determine the node efferent to these VMN neurons, that is involved in modulating energy expenditure, we employed electrophysiology and optogenetics experiments combined with measurements using tissue-implantable temperature microchips. Results Activation of the VMN neurons that express the steroidogenic ...