1n). These results strengthen our hypothesis that subunit stability depends on co-translational complex assembly and is not caused by loss of function. Interestingly, the homologous NatA and NatB complexes of two other yeast species (Schizosaccharomyces pombe and Candida albicans) display a similar ...
(1996) Two structurally different RNA molecules are bound by the spliceosomal protein U1A using the same recognition strategy. Structure , 4 , 621–631.Jovine L, Oubridge C, Avis JM, Nagai K 1996. Two structurally different RNA molecules are bound by the spliceosomal protein U1A using the ...
Receptor ligation triggers recruitment of the DD in the adapter protein FADD to the receptor through known interaction surfaces in the two DDs.1–3. In addition to a DD, FADD also contains an N-terminal death effector domain (DED) that is structurally similar to the DD.4 The DED of FADD...
RNAs are polymeric molecules comprised of different numbers and combinations of four major forms of ribonucleotide monomers distinguished by their corresponding nucleobases, adenine (A), guanine (G), cytosine (C), and uracil (U) (Fig. 4). An RNA molecule structurally differs from DNA in the pre...
Two integrin-type collagen receptors, αβand αβ, are structurally very similar. However, cells can concomitantly express the both receptors and they mig... P Nykvist,H Tu,J Ivaska,... - 《Journal of Biological Chemistry》 被引量: 217发表: 2000年 beta-Carotene exacerbates DNA oxidative da...
We have previously developed the first two generations of MASP-2 inhibitors by in vitro evolution of two unrelated canonical serine proteinase inhibitors. These inhibitors were selective LP inhibitors, but their nonhuman origin rendered them suboptimal lead molecules for drug development. Here, we ...
Consumers should keep in mind that it is not possible to separate mushroom mycelium from the substrate on which it’s grown under normal circumstances. Similar to yogurt, in which beneficial bacteria like Lactobacillus cultures milk, these two nutrient sources exist as a living, interconnected matrix...
[52],https://git.wageningenur.nl/medema-group/BiG-SCAPE). BiG-SCAPE builds sequence similarity networks for each BGC class. Within each network, similar BGCs are grouped into gene cluster families (GCFs) and two or more GCFs potentially encoding structurally similar compounds are grouped into ...
Extrinsic molecules, such as growth factors, cytokines, hormones and neurotransmitters are fundamental in the regulation of OL maturation19. Neural detachment, as well as other changes of the white matter in schizophrenia, appear to be related to abnormal oligodendrocytes. These alterations include ...
In addition, we have shown that these two genes are similarly regulated by GC-rich binding TFs, including the general TFs SP1 and SP3. Structurally, human Cosmc and T-synthase promoters have similarities as follows: CpG island with two GC-rich sequences proximal to the TSS, yet lacking a ...