It is arguable that were it not for this pandemic, mRNA vaccines would still be confined to research labs and biotech companies still willing to take the financial risk of investing in them. Normally these processes take years, or even decades, to be approved. One of the factors that acceler...
VACCINESHuman rotavirus (HRV) is still a leading cause of severe dehydrating gastroenteritis globally, particularly in infants and children. Previously, we demonstrated the immunogenicity of mRNA-based HRV vaccine candidates expressing the viral spike protein VP8* in rodent models. In the...
Two of them, one made by Pfizer and BioNTech and another made by Moderna are unlike any other vaccine. Instead of using weakened or inactivated components of the virus to activate the body’s immune response, these new vaccines use Messenger RNA or “mRNA”. CGTN’s Karina Huber explains ...
mRNA “vaccines” created by Moderna and Pfizer are gene therapies. They fulfill all the definitions of gene therapy and none of the definitions for a vaccine. This matters, as you cannot mandate a gene therapy against COVID-19 any more than you can force entire populations to undergo gene ...
mRNA-1273.815 Worldwide COVID-19 vaccine (pediatrics)KidCOVE mRNA-1273.815 Worldwide Pediatric RSV vaccine mRNA-1345 Worldwide Latent & Public Health Vaccines Latent Vaccines CMV vaccine mRNA-1647 Worldwide EBV vaccine (to prevent infectious mononucleosis) ...
A large case-control study of participants in the Veterans Administration (VA) health care system found that currently used SARS-CoV-2 vaccines are more than 95% effective in preventing confirmed infection. Because veterans are at particularly high risk given their older age and greater burden of...
The vaccines need to be shown to be safe and effective in large-scale human clinical trials, ahead of regulatory approval. However, as regulatory bodies around the world have already approved mRNA COVID-19 vaccines, there are far fewer regulatory hurdles than a year ago. ...
Second, there is a window to design and manufacture the vaccine as the patient recovers from surgery and undergoes adjuvant radiation therapy. Third, there is evidence to suggest that cancer vaccines will be most successful in the adjuvant setting, avoiding the tumor-induced regulatory networks and...
All SectionsAttenuated/Inactivated/Live and Vectored VaccinesCancer Vaccines and ImmunotherapyCellular/Molecular ImmunologyClinical ImmunologyCOVID-19 Vaccines and VaccinationDNA and mRNA VaccinesEpidemiologyHepatitis Virus VaccinesHIV VaccinesHuman Papillomavirus VaccinesHuman Vaccines and Public HealthInfluenza Virus ...
There are now 2 vaccines approved to prevent RSV-associated LRTI in adults 60 years of age and older. Studies of both the adjuvanted RSV vaccine and the RSVpreF vaccine yielded positive phase 3 efficacy and safety results. However, it is important to monitor the incidence of GBS as the vacc...