Therapeutic Communities were instituted in prisons for all the right reasons – there was a desperate need for effective substance abuse treatment programs and TC's were well-suited to the prison environment in many ways. The format and content of TCs was developed to address the antisocial man,...
A comprehensive methodology was developed for use in a series of process evaluations of seven therapeutic communities (TC's) for drug-involved offenders. Experiences garnered during these evaluations are related here to underscore the need for combined evaluation methodologies in order to provide an ...
TCF1+ PD-1+ CD8+ T cells have recently been shown to play a critical role in driving therapeutic responses to ICB in both mice and humans.26,27,28,29 Such cells are thought to be in a progenitor-like state and induced to differentiate into cells with cytotoxic function in response to ...
Explanatory and pragmatic attitudes in therapeutical trials. J Clin Epidemiol 2009;62:499–505. 49. Tunis SR, Stryer DB, Clancy CM. Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. JAMA 2003;290:1624–1632. 50. ...
These are the components of the drug that produce the intended therapeutic effect. Whether you take a brand-name drug or its generic version, you’re getting the same medicine where it counts[2]. B. Inactive Ingredients While the active ingredients must be the same, generic drugs may contain...
Together, our findings demonstrate a causal role for fungi in microbial ecology and host immune functionality, and therefore prompt the inclusion of fungi in therapeutic approaches aimed at modulating early life microbiomes.Similar content being viewed by others “Molding” immunity—modulation of ...
All could Exhibit 2: Attractive areas in emerging markets for innovative R&D Area Diseases specific to emerging markets 1 Previously neglected widespread indications that may become commercially viable 2 Genotype-specific diseases Examples of therapeutic areas and products ...
At the conference, emerging research on physiological, academic, cognitive, and therapeutic applications was reviewed. Conference participants concluded that, at present, most games are active enough for only modest vigorous energy expenditure. Other exergaming benefits include positive social interactions, ...
with the combinatorial effect of microbiota features taken into account, was also developed and further supported the putative role of gut microbiota. Here we aim to identify the microbiome associations with cachexia to open up the way for new therapeutic options for this critical medical condition ...
interventions could be directed. We do call for a reconsideration of the diagnostic algorithm of patients with HFpEF to routinely include CMR to assist therefore in defining the aetiology and identifying the patients with a higher risk of mortality; on whom further therapeutic interventions should ...