How are sister chromatids and homologous chromosomes different from each other? Homologous chromosomes a) are identical. b) are all the chromosomes from either parent. c) align on the metaphase plate in meiosis II. d) carry the same alleles. e) carry information for the same...
Where in the cell are chromosomes located? What is IMPORTANT about sister chromatids in metaphase? Why is the coiling of the chromosome necessary to accomplish cell division? Why does a chromosome appear during cell division? What other genes are on the Y chromosomes?
Attachment, or cohesion, between sister chromatids is essential for their proper segregation in mitosis and meiosis 1, 2. Sister chromatids are tightly apposed at their centromeric regions, but it is not known whether this is due to cohesion at the functional centromere or at flanking centric ...
(during anaphase). resulting in two sets of identical chromosomes. The cell divides, becoming two distinct cells, each with their own nucleus. Usually mitosis occurs with no problems, however, there have been cases where the chromatids do not separate properly. If the sister chromatids do not...
Point at which two sister chromatids are held together View Solution Crossing over takes place between : (a) Two sister chromatids (b) Two non-sister chromatids (c) Three homologous chromosomes (d) Four non-homologous chromosomes View Solution ...
(B) HeLa cells were released from double-thymidine block into nocodazole (3.3 μM) to synchronize in prometaphase. Cells were exposed to DMSO or RO3306 for 10 min in the presence of MG132 before fixation. Representative cells for DMSO and RO3306 were immunostained for DAPI (DNA marker), ...
Meiotic processes are potentially dangerous to genome stability and could be disastrous if activated in proliferative cells. Here we show that two key meiosis-defining proteins, the topoisomerase Spo11 (which forms double-strand breaks) and the meiotic cohesin Rec8, can dismantle centromeres. This ...
Sister-chromatid cohesionProtein sequencesAnaphase transitionMolecular-biologyCentromereMelanogasterSeparationRec8MetaphaseDivisionsBackground: Meiosis produces haploid gametes from diploid progenitor cells. This reduction is achieved by two successive nuclear divisions after one round of DNA replication. Correct ...
Aurora-B, as a component of the chromosomal passenger complex, localizes to the conden- sing chromosomes in prophase until the midbody in telo- phase, passing through the centromeres in metaphase and the central spindle in anaphase [11, 46]. Consistent with its spatio-temporal localization, ...
In addition to its prominent role in the cohesion complex, which encourages faithful sister chromatid pairing during mitosis, SMC1A has also been implicated in the DNA damage response52 and may be a potential spliceosome accessory factor53,54. SMC1A has also been identified as a mediator of ...