The present invention provides formula (I), this inhibitory activity PI 3-kinase γ isoforms can be used for treating the PI 3-kinase γ isoforms of the disease mediated by activation.ベルニー,ベンジャミン リチャードブルース,イアン...
pyrazine carboxylic acidsScope : Coffee is a complex mixture of over 1000 compounds, including diverse heteroaromatic compounds such as alkylpyrazines. Little is known about the intake, metabolism, and bodily distribution of these compounds. We therefore conducted a human intervention study to ...
Disclosed are polyhydroxybutylpyrazines of the general formulaIncluding their isomers, racemates, enantioners and salts thereof, as well as processes for preparing these compounds and medicaments containing them.BASHIARDES GEORGESCARRY JEAN-CHRISTOPHE...
Disclosed are polyhydroxybutylpyrazines of the general formulaIncluding their isomers, racemates, enantioners and salts thereof, as well as processes for preparing these compounds and medicaments containing them.BASHIARDES GEORGESCARRY JEAN-CHRISTOPHE...
Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitorsDisclosed are compounds of the formula (I)Harald EngelhardtDavide GianniChristian Smethurst
Pyrazine2-Ethylpyridine3-EthylpyridineOxidative stressDrug resistanceLung cancer is one of the few human diseases for which the primary etiological agent, cigarette smoke (CS), has been described; however, the precise role of individual cigarette smoke toxicant in tumor development and progression ...
Culture supernatants of Basfia succiniciproducens derived from the industrial production of succinic acid were surprisingly found to contain several alkylated pyrazines. Quantitation of the pyrazines was performed by means of dynamic headspace〨C㎝S after standard addition, and 2,3,5,6‐tetramethyl...
Water-dispersible IR-absorbing phthalocyanine dyes in which the benzene rings are fused to pyridine or pyrazine rings, suitable for use in inkjet inksdoi:US7138391 B2Dyes of this type are especially suitable for use in netpage and Hyperlabel systems.Simone Charlotte Vonwiller...
Novel derivatives of polyhydroxypyrazines, preparation thereof and pharmaceutical compositions in which these derivatives are comprisedThe invention concerns novel derivatives offormula (I) wherein: R1 represents the stereoisomeric forms of the chain -(CHOH)3-CH2-O-COR (II) and either R2 represents ...
insignis : 2-isopropyl-3-methoxypyrazine (IPMP), 2- isobutyl-3-methoxypyrazine (IBMP) and 2-( sec -butyl)-3-methoxypyrazine (SBMP). Their combined estimated total scent emissions per inflorescence ranged from 246 渭g.h -1 up to 6.2 mg.h -1 . Scented traps, individually baited with ...