Monocytes/macrophages are the main S100A9 producing cells in TRAMP prostate and human prostate tumors.Eva KällbergThomas VoglDavid LibergAnders OlssonPer BjörkPernilla WikströmAnders BerghJohannes RothFredrik IvarsTomas Leanderson
c Differential expression analysis for SARS-CoV-2 immune candidate genes in cDCs, Macrophages and Monocytes. *p-adjusted value < 0.1, **p-adjusted value < 0.05, p-adjusted value was Bonferroni adjusted from Seurat FindMarkers differential expression analysis using a negative binomial test ...
PMO localization is sustained in inflammatory foci where it enters macrophages, actively differentiating myoblasts and newly forming myotubes. We conclude that efficient PMO delivery into muscle requires two concomitant events: first, accumulation and retention of PMO within inflammatory foci associated with...
Successful tissue repair requires the activities of myeloid cells such as monocytes and macrophages that guide the progression of inflammation and healing outcome. Immunoregenerative materials leverage the function of endogenous immune cells to orchestrate complex mechanisms of repair; however, a deeper unde...
13 Moreover, monocytes/macrophages (the major Th1 effector leukocytes) are the dominant leukocytes in glomeruli and interstitium of patients with acute severe MPO-AAV.14 These data suggest that the key Th subsets in human MPO-AAV are Th1 and/or Th17. The major cytokines that direct and ...
The important contribution of monocytes and macrophages to cardiovascular disease and heart failure pathophysiology has attracted significant attention in ... N Glezeva,S Horgan,JA Baugh - 《Journal of Molecular & Cellular Cardiology》 被引量: 0发表: 2015年 "Where are the white heroes?" aspect of...
Monocytes were purified from peripheral blood mononuclear cells by adhesion and differentiated to MDMs for 7 days with 10 ng/mL macrophage colony-stimulating factor (Shenandoah Biotechnology, Warwick, PA) as described by Hedl et al.52 Messenger RNA Expression Total RNA was isolated, reverse ...
The cytokines interferon-γ (IFN-γ) and interleukin-4 (IL-4) further enhance macrophage polarization [63]. Based on their study of a mouse model, Weirather et al. demonstrated that regular T lymphocytes modulated the differentiation of monocytes and macrophages, subsequently influencing non-...
damaging-in-nature MPO products causing the cell death occurred via different pathways (see reviews [100,101]), influencing the cell membrane with final cell lysis, as demonstrated for red blood cells [102], or damaging the mitochondria of monocytes and macrophages with their necrotic death [103...
aare the most potent effector cells, followed by[translate] ainfection with Cryptococcus neoformans, despite[translate] aIn contrast, DCs possess fungicidal activity[translate] ainfections with most fungal pathogens, but[translate] amacrophages and monocytes are permissive for[translate]...