FUN14 domain-containing protein 1 (FUNDC1) is an integral mitochondrial outer-membrane protein, and mediates the formation of mitochondria-associated endoplasmic reticulum membranes (MAMs). This study aims to determine the contributions of FUNDC1-mediate
1d), and molecular simulations to identify structural biases of IDPs in vitro. We then examine the same constructs inside live cells using FRET microscopy (Fig. 1e). Finally, we perturb the cellular ensembles by subjecting cells to osmotic challenges that rapidly change cell volume and measure...
Molecular hydrogen (H2) is heralded as a future green energy carrier. In a biological context, this energy-rich gas already plays a central role in bioenergetics, and evolution has driven an elaborate H2 economy. Numerous bacteria, archaea, and microbial eukaryotes consume and produce H2 gas (H2...
A 0.175 M solution of X (molar mass = 199 g/mol) has a density of 1.101 g/mL. What is the molality of X in the solution? Calculate the molarity and molality of 37.0%(w/w) HCI with a density of 1.19 g . mL{-1}. The molecular mass of HCI is 36.46 g mol^{-1}. Calculate...
Plans for collection, laboratory evaluation, and storage of biological specimens for genetic or molecular analysis in this trial/future use {33} It is not applicable. All collected specimens will be used to evaluate condition alteration and safety of intervention and will not be used for other stu...
Suitable builders are also polymeric polycarboxylates; these are, for example, the alkali metal salts of polyacrylic acid or of polymethacrylic acid, for example, those having a relative molecular mass of from 500 to 70,000 g/mol. In the context of the present document, the molar masses ...
One half was Coomassie blue stained for protein molecular mass determination. In the other gel half, individual lanes were dissected into 2 mm slices; proteins were extracted and samples were counted for radioactivity. (A) The arrow points to the position of standard serum albumin. (B) Values ...
This circadian function is variable, and can be either light-dependent or -independent; the molecular origin of this difference is unknown. Type I animal cryptochromes are photoreceptors that entrain an organism's clock to its environment, whereas Type II (including mammals) regulate circadian timing...
Although tremendous progress has been made in the understanding of the structural transition of a number of amyloid proteins, detailed molecular insights into the misfolding process are difficult to obtain. In particular the onset of formation and details about intermediate species have proven elusive6...