Circles (J)¼females and squares (&)¼males. Solid symbols¼affected; unshaded symbols¼unaffected. Legend to the left of each generation indicates microsatellite marker used and list (top left) indicates genomic co-ordinates (chr 17) of each. The black portion of each haplotype bar ...
Circles, females; squares, males; black-filled, affected by a Lynch syndrome-type cancer; grey-filled, either affected by a cancer unlikely to be associated with Lynch syndrome, or diagnosis with a precursor lesion that could be Lynch syndrome-related. The type of neoplastic lesion and age of...
(B) Pedigree #H0992 through three generations. Solid squares and circles indicate affected males and females, respectively. (C) Segregation of Arg41Trp mutation in the pedigree. Since the transition from C to T resulted in the loss of restriction site for FauI (CCCGC(N)4/GGGCG(N)6; pro...
Rumer Willis’ Hollywood pedigree is impressive. Her father is action star Bruce Willis, and her mother is actress Demi Moore. Like her parents, she pursued a career in acting and was seen in a slew of movie roles. She was in the films "Whole Nine Yards" as well as "Hostage." On te...
Affected men and women are indicated by filled squares and circles, respectively. Normal individuals are shown as empty symbols. Deceased individuals are indicated with slashes (/). Figure 2. Slip-lamp and specular microscopy photographs of the affected individuals in Family (A). OD: right ...
Pedigree of UK Family SC32 in which a putative gene mutation has been found. (A) Open circles and squares indicate unaffected individuals. Blackened circles and squares indicate affected females and males respectively. The arrow indicates family proband (SC32.1) and NGS sequenced patients are indica...
Figure 2.Segregation analysis. Pedigree (upper panel) and respective segregation ofADAMTS13variant and COVID-19 status (lower panel) are shown. Squares represent male family members; circles represent females. A virus cartoon close to the individual symbol indicates individuals infected by SARS-CoV-...