such as cell membranes. This is also why lipids are a key component of hormones — chemical messengers that must travel through a liquid medium. Their strong molecular bonds make
Knockdown of lpin-1, which decreases the number of lipid droplets, led to a strong increase in lipid oxidation in middle-aged worms in both basal conditions and oleic acid supplementation (Fig. 6f). However, deficiency in seip-1, which decreases the number of lipid droplets (but increases ...
valent metal ions (e.g., Al3+[116]) and crosslinking via covalent bonds [22] have demonstrated some degree of success. It is also worthwhile to note that MoS2[124] and MXenes [118] can easily get oxidized in ambient conditions, which could limit their practical applications. 3Separation ...
Gp120 was modified with PenG and then modified with fluorophore Alexa Fluor 647 using a corresponding NHS ester. We further tetramerised biotinylated gp120 with streptavidin-phycoerythrin. These antigen-displaying probes were then used to sort the PenG-specific B cells on pre-gated non-naïve (...
selective fissile links to iminodiessigsure - ester bonds are basedLAM, KIT S.LEBL, MICHALKRCHNAK, VIKTORKOCIS, PETR
Crocin is a water-soluble antioxidant compound found in a variety of plant species [214,215]. Crocin can essentially decrease cytoplasmatic expression of Nrf2 while increasing nuclear expression of Nrf2 [216]. A study sought to investigate the effects of crocin and their methyl ester derivate dime...
arylsulfatase that is involved in the hydrolysis of sulfur ester-bonds common in algal sulfated polysaccharides, and genes used in, e.g., fatty acid biosynthesis, DNA replication and repair, and metabolism of purines and pyrimidines which are key components in nucleic acids (Fig. S2). Looking...
The phospholipase A2(PLA2) superfamily are ubiquitously found throughout the animal kingdom to catalyze the hydrolysis of ester bonds in a variety of different phospholipids producing lysophospholipids and free fatty acids that play important physiological roles [130]. The PLA2superfamily includes five...
ASchematic representation of peptide (top panel) and ester bonds (bottom panel). (B,C) Effect of replacing backbone amides with ester oxygens at positions lining Sextand Scenin bCLC-k (B) and CLC-0 (C) onPBr(black bars),PNO3(red bars) andPI(green bars). Nomenclature of α-hydroxy ...
The sterol was routinely examined as the 3-OH compound; but in some cases to show the number of hydroxyl groups in the structure, total sterol in the NLF was prepared as the TMS derivative as follows: The extracted sterol was converted to the TMS ester using 15 μl of N,O-Bis(...